An analysis is presented of how the permeability coefficient/octanol:water partition coefficient ratio for 33 different chemical substances crossing egg lecithin bilayers depends on the molecular volume of the substances. From this analysis we conclude that bilayers made from egg lecithin behave as soft polymers in their discrimination between permeants of different sizes and shapes.

Submit Manuscript | http://medcraveonline.com Abbreviations: ALT: Alanine Aminotransferase; LG: The Complex of Lecithin and Genistein by Synthesis; PMLG: The Physical Mixture of Lecithin and Genistein; UV: Ultraviolet; IR: Infrared Radiation; FT-IR: Fourier Transform Infrared; NMR: Nuclear Magnetic Resonance; SEM: Scanning Electron Microscopy; DSC: Differential Scanning Calorimetry; XRD: X-Ray ...

The effects of four different canola lecithins applied at proportions of 30 g fatty acid kgÿ1 diet were compared with diets containing either no additional lipid or the same amount of fatty acids from canola seed, pure canola oil and deoiled soy lecithin, respectively. Four types of canola lecithin with increasing dispersibility in water were used: raw; deoiled; deoiled/hydrolysed; and hydrolys...

BACKGROUND Lecithin has been widely sold as a dietary supplement. 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a phospholipid that does not exist in nature and has been used in vitro to study lipid binding. We tested DMPC in vivo in apolipoprotein (apo) E-null mice. METHODS AND RESULTS DMPC or soy or egg lecithin at 1.0 mg/mL was added to the drinking water of 4-week-old apoE-null fe...

In earlier studies, we prepared a docosapeptide, 1, designed with minimum homology as an amphiphilic alpha-helical model of apolipoprotein A-I (apo A-I) and described its lipid-binding characteristics, surface properties, and enzyme-activating ability. Although the affinity of 1 for egg lecithin unilamellar vesicles was comparable with that for the binding of apo A-I, the affinity of 1 for mixe...

Reversed micellar two-phase extraction is a developing technique for protein separation. Introduction of an affinity ligand is considered to be an effective approach to increase the selectivity and capacity of reversed micelles. In this article, Cibacron Blue F3G-A (CB) as an affinity ligand was immobilized to reversed micelles composed of soybean lecithin by a two-phase reaction. The affinity ...

The behavior of purified egg lecithin in water has been investigated in relation to the quantity of water present and the temperature. The complete binary phase diagram of egg lecithin-water is presented as well as X-ray diffraction data on selected mixtures. Dry egg lecithin is present in at least partially crystalline form until about 40 degrees C. Above this temperature it forms a "wax-like"...