Numerous types of age-related deficits in the nervous system have been well documented. While a distinction between general types of memories that are susceptible to compromise with advanced age has been fairly well agreed upon, it is often difficult to determine exactly which specific processes are detrimentally influenced. In this study, we used a paradigm that enabled us to distinguish betwe...

Parkinson’s disease (PD) is a neurodegenerative condition characterized by disruptions in both fine movement control and motor learning. Pathologically, these disruptions are attributed to the loss of dopamine neurons in the midbrain (a region of the brainstem). While it is known that changes in synaptic plasticity are important for learning new motor skills and maintaining memory throughout li...

objective : the major objective of this study was to determine the means and 95% confidence interval of normal 6 years old children's motor-verbal skills. based on the results of this study we could develop a measure to diagnose abnormal motor skills. in addition, in this follow-up study, we compared the first-graders' motor-verbal skills to their own skills one year earlier. method: ...

conclusions examining postural control as an endophenotype or early diagnostic marker of autism is a conceptual premise which should be considered in future investigations. at the end of the review, methodological recommendations on the assessment of postural control have also been provided. results individuals with asd have problems in maintaining postural control in infancy that well persists...

The purpose of this research was to compare the effects of drug therapy, perceptual motor training and a combination of drug therapy and perceptual motor training on gross and fine motor skills of 6 to 12 year-old Iranian attention deficit hyperactivity disorder children. Thirty-six attention deficit hyperactivity disorder children currently under treatment in three Iranian psychological-neurol...

Abstract The frontal lobes represent a large area, consuming approximately one-third of the cortical surface of the brain. This area is involved directly and indirectly across a wide spectrum of human thought, behavior and emotions. The irony of the frontal lobes may best be described as the area of the brain we know the most about but understand the least. For example, frontal lobe functioning...

BACKGROUND Children may be at higher risk than adults from pesticide exposure, due to their rapidly developing physiology, unique behavioral patterns, and interactions with the physical environment. This preliminary study conducted in Ecuador examines the association between household and environmental risk factors for pesticide exposure and neurobehavioral development. METHODS We collected d...

OBJECTIVE To describe the impaired fine-motor skills in patients with traumatic brain injury acquired in childhood. DESIGN A total of 165 patients with traumatic brain injury, aged 0-17 years, injured during the period 1987-1991, were identified. Fifteen years post-injury a questionnaire was sent to the patients. Twenty-six of the subjects had upper limb problems, 15 of whom agreed to partici...

OBJECTIVE The objective of this study was to provide an update of the evidence on the efficacy of gross motor development interventions in young children (0-5 years) from 2007 to 2015. METHODS Searches were conducted of six electronic databases: PUBMED, Medline (Ovid), ERIC (Ebsco), Embase, SCOPUS and Psychinfo. Studies included any childcare-based, preschool-based, home-based, or community-b...