For passive scattering proton therapy systems, neutron contamination is the main concern both from an occupational and patient safety perspective. The Mevion S250 compact proton therapy system is the first of its kind, offering an in-room cyclotron design which prompts more concern for shielding assessment. The purpose of this study was to accomplish an in-depth evaluation of both the shielding...

COVID-19 caused by severe acute respiratory syndrome (SARS) has accounted for huge collateral damage and as the virus is spreading faster this study deals with isolation rooms or negative pressure 12 more air changes per hour maintaining a difference of 2.5 pa which can help in reducing transmission from affected to not persons. ANSI/ASHRAE/ASHE Standard 170–2008 recommendations are followed ho...

In the area of motion planning, considerable work has been done on guarding problems, where “guards”, modelled as points, must guard a polygonal space from “intruders”. Different variants of this problem involve varying a number of factors. The guards performing the search may vary in terms of their number, their mobility, and their range of vision. The model of intruders may or may not allow t...

OBJECTIVE To determine the typical microbial bioburden (overall bacterial and multidrug-resistant organisms [MDROs]) on high-touch healthcare environmental surfaces after routine or terminal cleaning. DESIGN Prospective 2.5-year microbiological survey of large surface areas (>1,000 cm2). SETTING MDRO contact-precaution rooms from 9 acute-care hospitals and 2 long-term care facilities in 4 state...

Neurology® 2012;79:1 IV human recombinant tissue plasminogen activator (rt-PA) is the best proven and most effective treatment for acute ischemic stroke. The benefits of rt-PA are highly dependent on the time elapsed since stroke symptoms.1 Accordingly, the Brain Attack Coalition recommends that the time from emergency room arrival to initiation of rt-PA (that is, the “door-toneedle” time) shou...

BACKGROUND Rapid coronary recanalization following ST-elevation myocardial infarction (STEMI) requires effective anti-platelet and anti-thrombotic therapies. This study tested the impact of door to end of procedure ('door-to-end') time and baseline platelet activity on platelet inhibition within 24hours post-STEMI. METHODS AND FINDINGS 108 patients, treated with prasugrel and procedural bival...

OBJECTIVE To assess and reduce delays in coronary thrombolysis in patients with acute myocardial infarction. DESIGN Prospective, descriptive study using statistical process control. SETTING Interdisciplinary intensive care unit of a 300-bed community hospital. SUBJECTS Thirty-seven consecutive patients with acute myocardial infarction who were receiving thrombolytic therapy. INTERVENTIO...

Early detection of age-related disease symptoms in older people by the use daily activity data is one central challenges home sensor systems. This paper focuses on dementia scale classification from collected using sensors that can be deployed actual residential environments. Activity four (a door sensor, human motion location and sleep sensor) were obtained recording 56 adults living common re...