نتایج جستجو برای: flanking region

تعداد نتایج: 544338  

Journal: :Blood 2008
Michael B Boffa Deborah Maret Jeffrey D Hamill Nazareth Bastajian Paul Crainich Nancy S Jenny Zhonghua Tang Elizabeth M Macy Russell P Tracy Rendrik F Franco Michael E Nesheim Marlys L Koschinsky

Thrombin-activable fibrinolysis inhibitor (TAFI) is a plasma zymogen that acts as a molecular link between coagulation and fibrinolysis. Numerous single nucleotide polymorphisms (SNPs) have been identified in CPB2, the gene encoding TAFI, and are located in the 5'-flanking region, in the coding sequences, and in the 3'-untranslated region (UTR) of the CPB2 mRNA transcript. Associations between ...

2006
Rui Liu Yachun Wang Dongxiao Sun Ying Yu

The objective of this study was to screen single nucleotide polymorphisms (SNPs) of the chicken lipoprotein lipase gene (LPL), using 545 F1 hybrids developed from 4×4 diallel crossing of four chicken breeds, and to analyze the associations between polymorphisms of the LPL and chicken fat deposition traits. PCR-SSCP was used to detect SNPs in LPL. Fifteen sets of primers were designed to amplify...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1996
H Nishio A Dugaiczyk

The nucleotide sequence of the human alpha-albumin gene, including 887 bp of the 5'-flanking region and 1311 bp of the 3-flanking region (24,454 in total), was determined from three overlapping lambda phage clones. The sequence spans 22,256 bp from the cap site to the polyadenylylation site, revealing a gene structure of 15 exons separated by 14 introns. The methionine initiation codon ATG is w...

Journal: :American journal of physiology. Renal physiology 1998
Shinichi Uchida Tatemitsu Rai Hiroshi Yatsushige Yoshihiro Matsumura Masanobu Kawasaki Sei Sasaki Fumiaki Marumo

The rat ClC-K1 chloride channel is a kidney-specific member of the ClC chloride channel family found exclusively in the thin ascending limb of Henle's loop in the kidney. To gain insight into the mechanism(s) of kidney-specific expression of ClC-K1, a genomic clone that contains the 5'-flanking region of the rat ClC-K1 gene was isolated. A single transcription start site was located 84 bp upstr...

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