Flavonoids, including proanthocyanidins (PAs; also called condensed tannins), play a multitude of roles in plants (Winkel-Shirley, 2001). The presence of certain types of flavonoids in crops is associated with desirable and important agronomic traits; therefore, metabolic engineering of flavonoid biosynthesis has attracted considerable interest (Dixon, 2005). PAs are oligomers or polymers of fl...

Cisplatin (CP) as an important anti-tumor drug causes nephrotoxicity mainly by oxidative stress and renin-angiotensin system (RAS). Since flavonoids have high antioxidant activity and probable role in the inhibition of RAS, this study was designed to investigate the protective effect of hydroalcoholic extract and flavonoid fraction of Morus alba leaves on cisplatin-induced nephrotoxicity in rat...

Flavonols are potent naturally occurring antioxidants. Chemical oxidation reactions in combination with modern spectroscopic techniques have been employed to identify oxidized flavonoid products. Although many oxidized derivatives have been generated from commercially available starting materials, few studies have developed a sequence of flavonoid substrates with a particular hydroxylation patt...

Flavonoids are widely distributed in Plant Kingdom that act as free radical scavengers and play a vital role in combating various diseases through their antioxidant property. An attempt was made to evaluate the antioxidant property of free and bound flavonoids present in Wrightia tinctoria (Roxb) R.Br. leaves (Apocynaceae). An initial estimation of total phenolic and flavonoid content after met...

Total flavonoid and phenolic content, antiradical properties and external flavonoid profiles on extracts of six samples of flower heads of cultivated Arnica montana was assessed. The studied samples were compared in relation to location of cultivation, origin of the seeds, time of harvesting, method of propagation: in vitro and in vivo. Four flavonoid aglycones were detected of examined exudate...

Bulb color is an important consumer trait for onion (Allium cepa L., Allioideae, Asparagales). The bulbs accumulate a range of flavonoid compounds, including anthocyanins (red), flavonols (pale yellow), and chalcones (bright yellow). Flavonoid regulation is poorly characterized in onion and in other plants belonging to the Asparagales, despite being a major plant order containing many important...

BACKGROUND Ulva genus, an edible seaweed, and an important food source in many south-east Asian countries is also recognized by its synonymous name as Enteromorpha. OBJECTIVES This study was carried out to evaluate antioxidant activity, contents of total phenolics, and flavonoids of methanolic extracts of edible green seaweeds including Ulva clathrata (Roth) C. Agardh and three samples of Ulv...

Two recent case-control studies suggested that some flavonoid subgroups may play a role in preventing colorectal cancer. Previous prospective cohort studies generally reported no association; however, only a small subset of flavonoids was evaluated and partial flavonoid databases were used. We used the newly constructed U.S. Department of Agriculture flavonoid database to examine the associatio...

The complex [Cr(3,7diHF)3] ̈ 3H2O (3,7diHF is the monoanion of flavonoid 3,7-dihydroxyflavone) was synthetized and characterized by mass spectrometry, thermogravimetry, UV-Vis and FTIR spectroscopies. The data indicated that the coordination of the chromium(III) ion to the flavonoid increased its thermal stability.

Flavonoid-bearing probes have been designed and synthesized to explore their ability to selectively capture target proteins or biosynthetic enzymes under oxidative activation. A proof-of-concept study using biotinylated (epi)catechin-bearing affinity-based probes herein demonstrates the ability of these probes to capture the LDOX flavonoid enzyme using sodium periodate as the oxidant.