The purpose of this investigation was to prepare a gastro retentive drug delivery system of famotidine tablets. Floating tablets of famotidine were prepared employing lipid solid dispersion spray drying technique with gelucire 50/13 and compritol 888 along with HPMC K100M, lactose, sodium bicarbonate and citric acid. The floating tablets were evaluated for uniformity of weight, hardness, friabi...

Abstract. The purpose of this research was to develop and evaluate effervescent gastric floating tablets of propranolol HCl. The oral delivery of antihypertensive propranolol HCl was facilitated by preparing an effervescent floating dosage form which could increase its absorption in the stomach by increasing the drug's gastric residence time. In the present work, effervescent floating tablets w...

Floating arm injury represents a common yet complicated injury of the childhood severely associated with limb deformation and even morbidity, if not precisely addressed and credibly operated. Here, we report a rare floating upper limb case of a 9-year-old boy with multiple injuries of ipsilateral proximal humeral, supracondylar and distal radial limb. This is the first report to document such a...

Programs with floating-point computations are often derived from mathematical models or designed with the semantics of the real numbers in mind. However, for a given input, the computed path with floating-point numbers may differ from the path corresponding to the same computation with real numbers. A common practice when validating such programs consists in estimating the accuracy of floating-...

Floating dosage forms of acetylsalicylic acid, used for its antithrombotic effect, were developed to prolong gastric residence time and increase bioavailability. In the two-layer tablet formulation, hydroxypropyl methylcellulose (HPMC) of high viscosity and an effervescent mixture of citric acid and sodium bicarbonate formed the floating layer. The release layer contained the drug, direct table...

In this paper, the implementation of DSP modules such as a floating point ALU are presented and designed. The design is based on high performance FPGA "STRATIX III". The implementation is done after functional and timing simulation. The simulation tool used is Model Sim. The tool for synthesis and implementation is QuartusII [2]. The experimental results shows the functional and timin...

The closed-loop stability issue of finite-precision realizations is investigated for digital controllers implemented in floating-point arithmetic. Unlike the existing methods which only address the effect of the mantissa bits in floating-point implementation to the sensitivity of closed-loop stability, the sensitivity of closed-loop stability is analyzed with respect to both the mantissa and ex...

Floating-point arithmetic provides a fast but inexact way of computing geometric predicates. In order for these predicates to be exact, it is important to rule out all the numerical situations where floating-point computations could lead to wrong results. Taking into account all the potential problems is a tedious work to do by hand. We study in this paper a floating-point implementation of a f...

While hardware/software partitioning has been shown to provide significant performance gains, most hardware/software partitioning approaches are limited to partitioning computational kernels utilizing integers or fixed point implementations. Software developers often initially develop an application using built-in floating point representations and later convert the application to a fixed point...

Objective: The main purpose of this study is to prepare a floating micro articulated drug delivery system of ciprofloxacin by using non-aqueous solvent evaporation technique to increase the bioavailability and therapeutic effectiveness of the drug by prolonging its gastric residence time. Methods: Floating microparticles were prepared by using different low-density polymers such as ethyl cellul...