Theoretical models of the signal detected by a CCD camera during hyperspectral imaging with an integrating sphere are derived using Markov chains with absorbing states. The models provide analytical expressions that describe the real reflectance of the sample as a function of the detected signal at each pixel of the image. Validation of the models was done by using reflectance standards and tis...

PURPOSE To determine whether reflectance changes of the retina after electrical suprachoroidal-transretinal stimulation (STS) can be detected with a newly developed optical imaging fundus camera. METHODS Ten eyes of 10 cats were studied. A small retinal area was focally stimulated with electric currents passing between an active electrode placed in the fenestrated sclera and a reference elect...

The reported optical constants of uranium differ from that of vacuum significantly more than other elements do over the range of about 150 to 350 eV. This suggests that uranium could be used to produce high reflectance imaging mirrors for many soft x-ray applications. Elemental uranium is too chemically active to be used as a front surface mirror without protection. We computed the expected ref...

Fiber-free non-contact near-infrared (NIR) imaging devices using wide-field detectors are emerging apart from the contact and fiber-based NIR devices. Unlike the fiber-based devices that can image deep tissues, the fiber-free noncontact devices have been used only for subsurface imaging (≤1 cm) to date. A new compact (7 × 8 × 12 cm3) handheld Near-Infrared. Optical Scanner (NIROS) has been deve...

The present study summarizes recent developments in synthetic molecules and genetically encoded proteins acting as fluorescent probes for Cu( i ) imaging. Two approaches, i.e. , binding reaction based, are highlighted.

The successful development of safe and highly effective nanoprobes for targeted imaging and simultaneous therapy of in vivo gastric cancer is a great challenge. Herein we reported for the first time that anti-α-subunit of ATP synthase antibody, HAI-178 monoclonal antibody-conjugated fluorescent magnetic nanoparticles, was successfully used for targeted imaging and simultaneous therapy of in viv...

Resonon utilizes line-scan spectral imaging, where a scene is limited to one dimension with a slit, and then imaged off a diffraction grating to obtain spectral information for each pixel along the slit. A second spatial dimension is obtained by scanning the object as multiple frames are collected. Here, electrophoresis was used as the scanning mechanism, as illustrated in Figures 1 and 2. Prot...