The present study investigates morphological renal lesions in sinoaortic-denervated dogs 1 (n = 6) and 18 (n = 5) months after sinoaortic denervation compared with sham-operated controls (n = 8). After 1 month, a marked hyalinization and moderate thickening of the media of arterioles and small interlobular arteries were observed. These changes associated with edema and intimal thickening led to...

Detection and characterization of focal lesions in the cirrhotic liver may pose a diagnostic dilemma. Several benign and malignant lesions may be found in a cirrhotic liver along with hepatocellular carcinoma (HCC), and may exhibit typical or atypical imaging features. In this pictorial essay, we illustrate computed tomography and magnetic resonance imaging findings of lesions such as simple bi...

Alendronate-associated focal segmental glomerulosclerosis Sir, Alendronate sodium, a bisphosphonate and commonly used pharmacologic agent for postmenopausal osteoporosis, has been rarely linked to renal toxicity [1] but not in association with focal segmental glomerulosclerosis (FSGS). A 55-year-old Caucasian woman developed proteinuria and hypertension. Nine years earlier, she had been diagnos...