We investigated the cutaneous expression of genes and enzymes responsible for the multistep conversion of tryptophan to serotonin and further to melatonin. Samples tested were human skin, normal and pathologic (basal cell carcinoma and melanoma), cultured normal epidermal and follicular melanocytes, melanoma cell lines, normal neonatal and adult epidermal and follicular keratinocytes, squamous ...

Collision tumor represents the proximal coexistence of two histologically distinct tumors. The combination different types tumors in a single thyroid gland is extremely unusual. We reported case follicular carcinoma and papillary microcarcinoma occur independently as primary separated by normal tissue 59- year- old Saudi female, presented at clinic with goiter for months duration without sympto...

Follicular carcinoma of the thyroid rarely manifests itself as a distant metastatic lesion, and, when present, is usually found in flat bones. A soft tissue metastasis is extremely rare, and synchronous metastases to the bone and soft tissue is not reported in the literature so far. We report such a case of a 42-yr-old male, who presented with a goiter, scalp and forearm soft tissue swellings, ...

INTRODUCTION Most prognostic studies in differentiated carcinoma have included a high number of papillary carcinomas and few follicular carcinomas, and not all of their conclusions therefore apply to the latter. OBJECTIVE To analyze the prognostic factors of follicular thyroid carcinoma. PATIENTS AND METHODS SELECTION CRITERIA Patients with histological diagnosis of follicular carcinoma ...

Tumor of follicular infundibulum (TFI) is a rare benign cutaneous appendage tumor that does not have characteristic clinical features. It mainly present in the head, neck, and trunk as solitary lesion. In particular, TFI typically manifests plate-like proliferation with multiple thin epidermal connections comprise monomorphic cells. do represent characteristics, but significance because associa...

Hyperplastic or neoplastic proliferative lesions of thyroid follicular epithelium consist of a spectrum, ranging from nodular hyperplasia to undifferentiated (anaplastic) carcinoma, and usually present as palpable thyroid nodules. Thyroid nodules are a common occurrence in the general population, but only a small proportion of them are eventually diagnosed as carcinoma. The difficulty in object...

Introduction: Cauda equina secondary to metastatic follicular thyroid cancer of the lumbosacral area is a rare entity.   Case Report: We report an unusual case of a 52-year-old male who presented with backache, lower limb weakness, and perianal numbness. A CT-scan of the lumbosacral area showed an enhancing mass at the L4, L5 and S1 vertebrae. Histopathology after excision revealed a metast...

Objective: The study evaluated the prevalence and progression of different thyroid tumors in patients who referred to Shahid Sadoughi Hospital during 2005 to 2013, Yazd, Iran. Materials and Methods: In this retrospective follow-up study, cytopathological data of patients suffering from thyroid masses was collected during 2005-2013. Age and sex of patients were recorded. Results: Totally, 2055...