PubMed Citation Leukoencephalopathy is a structural alteration of cerebral white matter in which myelin suffers the most damage. Toxic leukoencephalopathy may be caused by exposure to a wide variety of agents, including cranial irradiation, therapeutic agents, drugs of abuse, and environmental toxins.1 Toxic leukoencephalopathy particularly involves white-matter tracts devoted to higher cerebra...

Non-compliance with prescribed medication is a major problem for elder people living alone in developed countries. Forgetfulness and confusion can lead to it, specially when multiple pathologies require a cocktail of different medications each delivered at different time intervals during different periods of time. Assistive technologies, a recent application area for a wide range of Artificial ...

This study aimed to assess the predictors of non-adherence to antihypertensive medications in northern United Arab Emirates. In a cross-sectional, multicentre study in Ajman Emirate, 250 patients with hypertension were randomly selected from outpatient clinics. Participants answered an interview questionnaire about sociodemographic and clinical data and completed the Morisky medication adherenc...

We regret to record the death of Dr. P. P. Johnson, of Yatton, .after a long and painful illness, borne with much fortitude. Dr. Johnson was 57 years of age, and was educated at Sedbergh, afterwards proceeding to Edinburgh University, where he took his degree in 1877. He practised for over nine years at Littleborough, in Lancashire, and for a short time in Starbotton, Yorkshire, and came to Yat...

OBJECTIVE to identify salient behavioral, normative, control and self-efficacy beliefs related to the behavior of adherence to oral antidiabetic agents, using the Theory of Planned Behavior. METHOD cross-sectional, exploratory study with 17 diabetic patients in chronic use of oral antidiabetic medication and in outpatient follow-up. Individual interviews were recorded, transcribed and content...

BACKGROUND Development of resistance to first line antimalarials led to recommendation of artemisinin based combination therapies (ACTs). High adherence to ACTs provided by community health workers (CHWs) gave reassurance that community based interventions did not increase the risk of drug resistance. Integrated community case management of illnesses (ICCM) is now recommended through which chil...

The use of multiple medicines is frequent among the elderly. Although such practice is usually necessary, it predisposes to risks of adverse events and drug interaction. The present study was intended to verify the characteristics of medication among the elderly in relation to socio-demographic profile, the most commonly used drug classes, and treatment adherence. This was a descriptive study t...

Background Patients with schizophrenia are managed with antipsychotics and other psychotropic medications. Objectives This study aimed to assess the commonly prescribed psychotropic medications for patients with schizophrenia, explore the types of therapeutic monitoring that were performed, and find out whether the side effects experienced by the patients played any role in their adherence be...

Improving medication adherence may have a greater influence on the health of our population than in the discovery of any new therapy. Patients are nonadherent to their medicine 50% of the time. Although most physicians believe nonadherence is primarily due to lack of access or forgetfulness, nonadherence can often be an intentional choice made by the patient. Patient concealment of their medica...

PURPOSE To investigate self-reported barriers to medication adherence among chronically ill adolescents, and to investigate whether barriers are unique to specific chronic diseases or more generic across conditions. METHODS A systematic search of Web of Science, PubMed, Embase, PsycINFO, and CINAHL from January 2000 to May 2012 was conducted. Articles were included if they examined barriers t...