The operational concept of aerodynamic formation flight, also referred to as aircraft wake-surfing for efficiency (AWSE), has high potential in terms fuel savings and climate impact mitigation. In order implement this concept, many technological challenges have be coped with. As the consumption during a mission strongly depends on successful execution AWSE, existing uncertainties regarding flig...

This paper introduces a new kind of operational multi-crew scheduling problem which consists in simultaneously modifying, as necessary, the existing flight departure times and planned individual work days (duties) for the set of crew members, while respecting predefined aircraft itineraries. The splitting of a planned crew is allowed during a day of operations, where it is more important to cov...

This paper reviews the interventions to stabilize calcium balance and bone metabolism and prevent bone loss in astronauts during space flight. Weightlessness during space flight results in calcium, vitamin D, and vitamin K deficiency, increases urinary calcium excretion, decreases intestinal calcium absorption, and increases serum calcium level, with decreased levels of serum parathyroid hormon...