Two deletion-substitution mutations of phage lambda, spi-113 and spi-274, are shown to remove about half of the rightward operator OR. Physiological studies show that spi-113 is still repressible. Thus, the 50 or so nucleotides of OR deleted in this mutant are not absolutely essential for repression. prm-116, which inactivates the promoter essential for the maintenance of lambda repressor synth...

While diffuse large-cell lymphoma (DLCL) is considered to be highly curable with current therapy, treatment failures are observed even with intensive combination chemotherapy regimens. In order to study the prognostic significance of actual dose intensity of chemotherapy in DLCL, we retrospectively analyzed 115 previously untreated patients treated as Stanford between 1975 and 1986 with cycloph...

BACKGROUND Diagnosis of obstructive sleep apnea syndrome (OSAS) by ambulatory systems is a growing practice in view of the large number of patients awaiting correct diagnosis. The Watch PAT100 (WP100) [Itamar Medical; Caesarea, Israel] is a portable device based on the peripheral arterial tone (PAT) signal, and is designed for unattended home sleep studies. OBJECTIVES To evaluate the efficacy...

• Regulated deficit irrigation was assessed in almond, peach and plum over 3 years. Fruit-growth slowdown stages are appropriate periods to apply irrigation. Peach yields were unaffected under a regulated of 75% ETC. 50% ETC maintained almond plum. Fruit quality improved </ListItem...

Salmonella enterica serovar Typhimurium (S. Typhimurium) is a major intestinal pathogen of both humans and animals. Salmonella pathogenicity island 1 (SPI-1)-encoded virulence genes are required for S. Typhimurium invasion. While oxygen (O2) limitation is an important signal for SPI-1 induction under host conditions, how the signal is received and integrated to the central SPI-1 regulatory syst...

BACKGROUND Determination of relationships between transcranial Doppler (TCD)-based spectral pulsatility index (sPI) and pulse amplitude (AMP) of intracranial pressure (ICP) in 2 groups of severe traumatic brain injury (TBI) patients (a) displaying plateau waves and (b) with unstable mean arterial pressure (MAP). METHODS We retrospectively reviewed patients with severe TBI and continuous TCD m...

Clustering analysis is the problem of partitioning a set of objects O = {o1... on} into c self-similar subsets based on available data. In general, clustering of unlabeled data poses three major problems: 1) assessing cluster tendency, i.e., how many clusters to seek? 2) Partitioning the data into c meaningful groups, and 3) validating the c clusters that are discovered. We address the first pr...

OBJECTIVE To investigate the relation between measures of pain threshold and symptoms of distress to determine if fibromyalgia is a discrete construct/ disorder in the clinic. METHODS 627 patients seen at an outpatient rheumatology centre from 1993 to 1996 underwent tender point and dolorimetry examinations. All completed the assessment scales for fatigue, sleep disturbance, anxiety, depressi...

In the state of Sinaloa, rainfall presents considerable irregularities, and climate is mainly semiarid, which highlights importance studying sensitivity various indices meteorological drought. The goal to evaluate four drought from five weather stations in Sinaloa for prediction rainfed maize yield. Using DrinC software data period 1982–2013, following were calculated: standardized precipitatio...