The genome of Mycobacterium massiliense M172, isolated from a human sputum sample, was sequenced using Illumina GA IIX technology and found to contain 5,204,460 bp, including putative genes for virulence and antibiotic resistance as well as a 92-kb genomic region most likely to correspond to a mycobacteriophage.

BACKGROUND Intraoperative blood pressure (BP) is a concern in daily clinic anesthesia and contributes to the differences in clinical outcome. We conducted a randomized controlled trial (RCT) to compare the effect of high vs. low mean arterial pressure (MAP) levels on clinical outcomes and complications in elderly patients under general anesthesia (GA). METHODS In this multicenter, randomized,...

Aristaless-like homeobox 4 (ALX4) gene is an important transcription regulator in skull and limb development. In humans and mice ALX4 mutations or loss of function result in a number of skeletal and organ malformations, including polydactyly, tibial hemimelia, omphalocele, biparietal foramina, impaired mammary epithelial morphogenesis, alopecia, coronal craniosynostosis, hypertelorism, depresse...

We have previously demonstrated that the cell-specific expression of Kv1.5 promoter is regulated by a silencer (Kv1.5 repressor element; KRE) containing a dinucleotide-repetitive element, (GT)19(GA)1(CA) 15(GA)16. Electromobility gel shift assays (EMSAs) of KRE with GH3 nuclear extracts detected a unique DNA-protein complex, which was not detectable in Chinese hamster ovary or COS-7 cells. We f...

When the Neural Network model is used to interpolate the non-circular curves, there are shortcomings of converging slowly and getting into the local optimum easily. A novel numerical control interpolation algorithm based on the GA (Genetic Algorithms) and NN (Neural Network) was introduced for the ultra-precision machining of aspheric surfaces. The algorithm integrated the global searching of G...

This paper employs chaos theory into power load forecasting. Lyapunov exponents on chaos theory are calculated to judge whether it is a chaotic system. Delay time and embedding dimension are calculated to reconstruct the phase space and determine the structure of artificial neural network ANN . Improved back propagation BP algorithm based on genetic algorithm GA is used to train and forecast. F...

BACKGROUND General anesthesia (GA) for acute stroke interventions may be associated with inferior functional outcomes. Our goal was to identify physiologic parameters that mediate this association. METHODS Consecutive patients treated at our institution between August 2007 and December 2010 were identified from a prospective database. Clinical data were then extracted by retrospective chart r...

Artificial Neural Networks (ANN) trained using backpropagation (BP) algorithm are commonly used for modeling material behavior associated with non-linear, complex or unknown interactions among the material constituents. Despite multidisciplinary applications of back-propagation neural networks (BPNN), the BP algorithm possesses the inherent drawback of getting trapped in local minima and slowly...

The kidney plays an important role in salt and blood pressure (BP) homeostasis. In previous studies, variants in the genes for alpha-adducin (ADD1), WNK1, and NEDD4L, which all regulate renal sodium absorption, have been associated with increased BP. However, findings have been inconsistent. We tested whether this is because of physiological interactions between the effects of variants in these...

This paper presents a neural networks based approach in order to estimate the start-up time of turbine based power plants. Neural networks are trained with a hybrid approach, indeed we combine the Back-Propagation (BP) algorithm and the Simple Genetic Algorithm (GA) in order to effectively train neural networks in such a way that the BP algorithm initializes a few individuals of the GA's popula...