PURPOSE To develop an intraoperative multimodal imaging system (IMIS) for surgical guidance, combining gamma ray scintigraphy with a video camera system for simultaneous real-time visible and near infrared fluorescence (NIRf) imaging. METHODS The gamma camera component has been tested in a pilot human study for intraoperative SLN biopsy in melanoma patients. To characterize the optical compon...

Existing protocols for assessing the performance characteristics of large field-of-view (LFOV) gamma cameras can be inappropriate and require modification for use with small field-of-view (SFOV) gamma camera systems. This communication proposes a generic scheme suitable for evaluating the performance characteristics of SFOV gamma cameras, based on modifications to the standard procedures of NEM...