ABSTRACT: The genetic improvement of a plant to produce high-yielding varieties depends on variability. It is widely known that the mangosteen (Garcinia mangostana L.) does not have variability because it has an apomictic reproductive mechanism. Analysis diversity can be carried out by analysis similarities and clusters between accessions plants or with their close relatives Garcinia genus. Thi...

Garcinia parvifolia belongs to the same family as mangosteen (Garcinia mangostana), which is known locally in Sabah as "asam kandis" or cherry mangosteen. The present study was conducted to determine the phytochemicals content (total phenolic, flavonoid, anthocyanin, and carotenoid content) and antioxidant and acetylcholinesterase inhibition activity of the flesh and peel of G. parvifolia. All ...

Natural products of the caged Garcinia xanthones (CGX) family are characterized by a unique chemical structure, potent bioactivities and promising pharmacological profiles. We have developed a Claisen/Diels-Alder reaction cascade that, in combination with a Pd(0)-catalyzed reverse prenylation, provides rapid and efficient access to the CGX pharmacophore, represented by the structure of cluvenon...

The antioxidant and antimicrobial activities of the extracts from peel, leaves, and bark of mangosteen (Garcinia mangostana L.), and some essential oils such as cinnamon and citrus were investigated. The antioxidant activities (IC50) of peel, leaves, and bark extracted, which were evaluated by DPPH method, were 5.94, 9.44, and 6.46 μg/ml, respectively. Either cinnamon or citrus essential oil sh...

This study aimed to investigate the anti-obesity effects of yogurt fermented by Lactobacillus plantarum Q180 in diet-induced obese rats. To examine the effects, male Sprague-Dawley rats were fed on six different diets, as follows: Group A was fed an ND and orally administrated saline solution; Group B, an HFD and orally administrated saline solution; Group C, an HFD and orally administrated yog...

southern part of Nigeria and other west African nations. Examinations of the liver, kidney and duodenum of rats fed a diet containing 10% w/w of dry powdered seed of the kola for 6 weeks has been reported as revealing some useful histological alterations in these organs. In some Nigerian houses it is served as a substitute for the true kola nuts (Cola nitida and Cola acuminata). It has a bitter...

Two new xanthones, cowaxanthones G (1) and H (2), and 23 known analogues were isolated from an acetone extract of the leaves of Garcinia cowa. The isolated compounds were evaluated for cytotoxicity against three cancer cell lines and immortalized HL7702 normal liver cells, whereby compounds 1, 5, 8, and 15-17 exhibited significant cytotoxicity. Cell cycle analysis using flow cytometry showed th...

The U.S. Patent and Trademark Office recently issued U.S.Patent No. 8,337,911 B2 which is entitled “Herbal formulation for the prevention and management of Type-2 Diabetes mellitus and vascular complications associated with diabetes”. This patent was assigned to SRM University, Kattankulathur, India contains claims for treatment of the vascular complications associated with type-2 diabetes mell...