Cardiovascular disease is a complex and multifactorial disease characterized by such factors as high cholesterol, hypertension, reduced fibrinolysis, increase in blood-clotting time and increased platelet aggregation. Dietary therapy is the first step in the treatment of hyperlipidemia; garlic has been used medicinally for centuries and is still included in the traditional medicine of many cult...

Abstract: Influenza virus is the most important cause of annual morbidities and mortalities worldwide with numerous antigenic drifts and shifts. Inaccessibility to effective drugs and vaccines has made world health authorities to be interested in traditional medicine in order to prevent spread of the infectious agent. Garlic is one of the most famous of all plants in human history. It has bee...

BACKGROUND Hypercholesterolemia is associated with an increased risk of heart disease. In this study, we investigated the antihyperlipidemic effects of garlic (Allium sativum L.) in rat models of hypercholesterolemic. METHODS Wistar male rats were randomly divided into 4 diet groups with garlic supplementation. Male Wistar rats were fed by standard pellet diet (group I), standard diet supplem...

OBJECTIVE(S) The present study was designed to investigate the antibacterial function and pharmacological effect of elephant garlic (Allium ampeloprasum var. ampeloprasum) on U2OS human osteosarcoma cells. MATERIALS AND METHODS Seven kinds of bacteria were reconstituted, inoculated and tested in this research to evaluate elephant garlic antibacterial activity. By the means of FACS analysis, c...

Dithranol is a potent agent in treating psoriasis but its adverse effects on intact skin have limited its usage. There are many proposed mediators for its adverse effects including prostaglandins, histamine, platelet activating factor and free radicals. In this study we examined the effect of different agents (diazepam, terfenadine, indomethacin and garlic extract) on dithranol-induced skin dam...

Garlic extract is gaining increasing acceptance as an antimicrobial and anti-inflammatory agent and as a folk remedy on wound healing. We studied the effect of crushed garlic extract on wound healing in albino rats. 20 male albino rats had a linear 3 cm incision made over skin of back. The animals were randomly divided into two experimental groups, as control and treatment. Animals of control g...

background: the production of nitric oxide (no) is important in the final outcome of leishmaniasis in animal models. objective: the efficacy of garlic therapy and a combination of garlic and vitamin a were compared with an antimonial drug (glucantime) to assess healing and regulation of no release in mice infected with leishmania major . methods: the mice were subjected to 3 ´ 10 5 promastigote...

in order to study the effect of garlic crude extract on growth rate and histopathology of liver, kidney and intestinal bulb, 120 fishes with initial mean weight of 95±22 g were divided to four groups. they were fed with 0, 10, 20 and 40 g/kg garlic crud extract in food for 1 month. at the end of experimental period, the growth rate was estimated and samples from liver, kidney and intestinal bul...

Introduction: Garlic (Allium Satiyum) is a plant widely used in traditional medicine. Its anti-hypertensive, lipid lowering, oxidative activities, anti-viral, anti-bacterial, anti-fungal properties have been proven. It has a tonic effects on stomach but its effects on gastric secretion is not known. Propose of study: To investigate the effect of garlic extract on basal and pentagastrin stimulat...