Inflammation is a risk factor for the development of many types of neoplasia, including skin, colon, gastric, and mammary cancers, among others. The role of inflammation in lung neoplasia is influenced by many other factors. Asthma is a very common chronic disease that occurs in all age groups. Some studies reported a positive association between asthma and lung cancer, even in never-smoking pa...

BACKGROUND beta-Defensins are a newly identified family of antimicrobial peptides that are expressed by epithelia on mucosal surfaces where their production is augmented by infection or inflammation. Helicobacter pylori colonises the gastric epithelium causing persistent gastric inflammation leading to antral and corpus gastritis, and peptic ulcer disease. AIMS To evaluate the role of beta-de...

Background: β-Defensins are a newly identified family of antimicrobial peptides that are expressed by epithelia on mucosal surfaces where their production is augmented by infection or inflammation. Helicobacter pylori colonises the gastric epithelium causing persistent gastric inflammation leading to antral and corpus gastritis, and peptic ulcer disease. Aims: To evaluate the role of β-defensin...

Chronic inflammation caused by infection with Helicobacter pylori and autoimmune gastritis increases an individual's risk of developing gastric cancer. More than 90% of gastric cancers are adenocarcinomas, which originate from epithelial cells in the chronically inflamed gastric mucosa. However, only a small subset of chronic gastritis patients develops gastric cancer, implying a role for genet...

Splenic vein thrombosis is a relatively common finding in pancreatitis. Gastric variceal bleeding is a life-threatening complication of splenic vein thrombosis, resulting from increased blood flow to short gastric vein. Traditionally, splenectomy is considered the treatment of choice. However, surgery in necrotizing pancreatitis is dangerous, because of severe inflammation, adhesion, and bleedi...

Dear Editor: Recent data provide new roles for alpha-fetoprotein (AFP) in controlling the autoimmune inflammation associated with experimental autoimmune encephalomyelitis (EAE), thereby suggesting a therapeutic potential for recombinant AFP in EAE and other relative autoimmune disorders such as multiple sclerosis (MS) or rheumatoid arthritis1. Although this suggestion might be correct, it poss...