objective(s):mirnas have been proposed to be key regulators of tumorigenesis, progression and metastasis. however, their effect and prognostic value in gastric cancer is still poorly known. materials and methods: gastric cancer cell lines were cultured. tissue samples obtained from 36 gastric cancer patients were used for quantitative real-time pcr (qrt-pcr) analysis. the tissue microarrays (tm...

abstract       background and objective: baba2 and hpa genes are involved in adherence of helicobacter pylori (h.pylori) to gastric mucosal tissue. this study aimed to investigate the frequency of these genes in isolates of h. pylori from gastric biopsies and their relationship with gastritis, peptic ulcer and gastric cancer.       methods: gastric biopsy samples were obtained from patients wit...

abstract injection of sulpiride (d2 receptor antagonist, antipsychotic drug) into vmn hypothalamus, increased gastric volume secretion and decreased gastric ph. the present study the effect of sch23390 (d1 dopamine receptor antagonist) on the gastric acid secretion and its acidity were studied. 70 rats were divided into 7 groups: two control groups, two sham groups given medicine solvents, a sc...

background: to asses the status of two representative genes of cag pai i.e caga and cage of helicobacter pylori strains infecting iranian patients suffered from various clinical outcomes using one-step pcr. methods: a total of 120 h. pylori infected patients including non-ulcer dyspepsia, nud (n=81), peptic ulcer disease, pud (n=17), and gastric carcinoma, gc (n= 22) referred for endoscopy or g...

Introduction: It has been reported the alkaline response of pancreas to duodenal acidification is partly mediated through duodenal release of H2S, but till now the effect of duodenal acidification on gastric H2S release has not been investigated. Therefore, the present study designed to evaluate the effects of duodenal acidification on gastric H2S release and level of mRNA expression of cys...

introduction: lymphoma may involve the gastrointestinal tract either primarily or as a manifestation of extensively disseminated systemic disease. stomach being the most frequent site of primary gastroin-testinal lyphoma, followed by the small bowel and colon respectively (1&2&3). for diagnosis of pi-mary small intestinal lymphoma (psil), one most satisfies the criteria specified by dawson and ...

abstract background: gastric cancer is one of the most common cancers in our country. recent studies have shown that adenocarcinoma of the cardia and distal stomach has increased in the past 25 years. however demographic data is lacking in this regard. methods: this study is a retrospective case series study. all records from 460 consecutive patients who were documented pathologically to have g...

conclusions gastric pouch is a suitable segment for bladder cystoplasty and neobladder. continence is mostly related to the capacity of pouch. results postoperative complications were rare. continence was defined as bladder capacity over 400 ml. their follow-up period ranged from five months up to writing the article. one of the studied cases is still alive and awaiting renal transplantation. m...

Background & Objective: Gastric cancer is the second most frequent cause of cancer death worldwide, despite differences in incidence around the world. The majority of gastric cancer cases concern gastric adenocarcinoma, which has a fairly high 5-year survival rate when coupled with early-stage diagnosis. Versican, a member of the aggregating chondroitin sulfate proteoglycans fa...