To date, most concepts on the frequency of gastro-oesophageal reflux episodes and the efficiency of the antireflux barrier have been based on inferences derived from measurement of oesophageal pH. The development of intraluminal impedance monitoring has highlighted the fact that pH monitoring does not detect all gastro-oesophageal reflux events when little or no acid is present in the refluxate...

M.D. (Pp. xii + 566; figs. 415. 144s.) London: Bailliere, Tindall & Cox, 1958. THIS work covers every conceivable aspect of obstruction in the gastro-intestinal tract from the cesophagus to the anal canal in a truly encycloprdic manner. The book contains a tremendous amount of information and approximately 1,700 references in the bibliography. It is refreshing here to note that the authors incl...

Professor of Greek tells me that he truly believes the classics have made him what he is. This is a very grave statement, if well founded. Indeed, I have heard the same argument from a great many Latin and Greek scholars. They all claim, with some heat, that Latin and Greek have practically made them what they are. This damaging charge against the classics should not be too readily accepted. In...

Gastro-esophageal reflux (GER) is a physiological phenomenon occurring in every individual. Gastro-esophageal reflux Disease (GERD) is a pathological condition where the reflux into the esophagus causes local changes and aspiration of the gastric contents in to the lungs can cause serious, even life threatening conditions. GERD is common but under-diagnosed condition in children. There are fund...

CHAIRMAN. Have you any idea of the success rate of diagnosis of carcinoma of the pancreas. Are there any false positives? HERLINGER. I haven't attempted to prove any diagnostic abilities but I was quite happy to go back after I had been proved wrong, to see whether I could have been right if I had known more, and making use of this retrospective diagnosis I would say that the correlation betwee...

BACKGROUND We evaluated AMG 386, an investigational peptibody that neutralizes the interaction between angiopoietins-1 and -2 and the Tie2 receptor, combined with cisplatin/capecitabine (CX) as first-line treatment for metastatic gastro-oesophageal cancer. PATIENTS AND METHODS Patients with metastatic gastric, gastro-oesophageal junction, or distal oesophageal adenocarcinoma were randomized 1...

Gastro-esophageal reflux (GER) is common in infants and children and has a varied clinical presentation: from infants with innocent regurgitation to infants and children with severe esophageal and extra-esophageal complications that define pathological gastro-esophageal reflux disease (GERD). Although the pathophysiology is similar to that of adults, symptoms of GERD in infants and children are...

In adults, most intussusceptions develop from a lesion, usually a benign or malignant neoplasm, and can occur at any site in the gastrointestinal tract. Intussusception in the proximal gastrointestinal tract is uncommon, and gastro-gastric intussusception is extremely rare. We present a case of gastro-gastric intussusception secondary to a primary gastric lymphoma. An 82-year-old female patient...

PURPOSE To validate the feasibility of a single-fraction high-dose-rate brachytherapy (HDRBT) boost for prostate cancer using real-time transrectal ultrasound (TRUS) based planning. MATERIAL AND METHODS From August 2012 to September 2015, 126 patients underwent a single-fraction HDRBT boost of 15 Gy using real-time TRUS based planning. External beam radiation therapy (EBRT) (37.5 Gy/15 fracti...

OBJECTIVES To determine the upper gastrointestinal (UGI) toxicity of nonsteroidal anti-inflammatory drugs (NSAIDs), in African-American and Hispanic elderly patients. SETTING Inner-city community hospital. METHODS Retrospective review of records of 698 patients, 65 to 101 years old. Upper gastrointestinal (UGI) symptoms and history of NSAIDs consumption were recorded over a 12-year period. ...