BACKGROUND AND OBJECTIVES The Initiating Dialysis Early and Late study showed that planned early or late initiation of dialysis, based on the Cockcroft and Gault estimation of GFR, was associated with identical clinical outcomes. This study examined the association of all-cause mortality with estimated GFR at dialysis commencement, which was determined using multiple formulas. DESIGN, SETTING...

We have read the article “Vitamin D level and extent of coronary stenotic lesions in patients with first acute myocardial infarction” by Goleniewska et al. [1]. Although vitamin D level is the most important condition for musculoskeletal system in children, it is associated with inflammatory status in adults at the present time [2]. Vitamin D has potentially improved the development of atherosc...

Objective: To determine frequency and patterns of coronary artery disease in patients with glomerular hyper filtration (GHF), presented acute syndrome (ACS). Study Design: Cross Sectional, Retrospective study. Setting: Tertiary Healthcare Centre, Karachi. Period: July 2018 to 2021. Material & Methods: Twelve hundred sixty seven undergone Coronary angiography (CAG) for ACS having estimated r...

Background: Numerous equations are applied in order to estimate the glomerular filtration rate (GFR). Objectives: This study aimed spot optimal equation that accurately estimates GFR and, therefore, chronic kidney disease (CKD) stage renal transplant patients. Methods: cross-sectional was conducted on 58 Their venous blood samples were obtained for serum creatinine and cystatin C determination ...

OBJECTIVES Cystatin C is emerging as an endogenous marker of glomerular filtration rate. This study sought to assess the usefulness of serum cystatin C as a marker of glomerular filtration rate in comparison with serum creatinine and serum creatinine-based glomerular filtration rate estimations in voluntary kidney donors. MATERIALS AND METHODS Serum cystatin C and serum creatinine were estima...

INTRODUCTION AND OBJECTIVES New oral anticoagulants require dosing adjustment according to renal function. We aimed to determine discordance in hypothetical recommended dosing of these drugs using different estimated glomerular filtration rate equations in patients with atrial fibrillation. METHODS Cross-sectional analysis of 910 patients with atrial fibrillation and an indication for oral an...

AIMS Atrial fibrillation (AF) is common among patients with impaired renal function. Apixaban, a novel oral anticoagulant with partial renal excretion, was compared with warfarin and reduced the rate stroke, death and bleeding in the ARISTOTLE trial. We evaluated these outcomes in relation to renal function. METHODS AND RESULTS Baseline glomerular filtration rate (GFR) was estimated using the...

objective: measurement of glomerular filtration rate (gfr) is the best determinant in assessment of kidney function for diagnostic and therapeutic purposes. as extremely accurate methods of gfr measurement (i.e. inulin clearance) are expensive and time-consuming and due to limitations of the 24 hour urine collection method, some formula have been developed for the gfr measurement. here we have ...