Assessment of the retinal nerve fiber layer (RNFL) is appealing for use in clinical trials of glaucoma neuroprotection, as it is directly correlated with loss of ganglion cells, which is assumed to be a primary event in glaucomatous damage. Qualitative assessment of the RNFL includes ophthalmoscopy, color stereophotography, and red-free monochromatic photography. In contrast, confocal scanning ...

BACKGROUND The aim of this study was to evaluate the sensitivity, specificity, and likelihood ratio of standard diagnostic parameters C/D, NFI, and MD and their applicability in diagnostics of primary open-angle glaucoma. MATERIAL AND METHODS This study included 194 subjects (371 eyes), ages 30 to 65 years old, who underwent full ophthalmologic examination and HRT, GDx, and FDT examinations. ...

Monitoring glaucoma patients and ensuring optimal treatment requires accurate and precise detection of progression. Many glaucomatous progression detection strategies may be formulated for Scanning Laser Polarimetry (SLP) data of the local nerve fiber thickness. In this paper, several strategies, all based on repeated GDx VCC SLP measurements, are tested to identify the optimal one for clinical...

Testosterone is a steroid hormone, which has a crucial role for development of the brain and its functions, including behavior and cognitive abilities. It influences the development of reproductive system and secondary sexual characteristics, distribution of fat and hair growth [1]. In men, testosterone is mainly produced by Leydig cells of the testes [2], while in females it is mainly generate...

Using first-principles calculations, based on disordered local moment theory, combined with the selfinteraction corrected local spin density approximation, we study magnetic interactions in GdX intermetallics for X = Cu, Zn, Ga, Cd, and Mg. Our predicted magnetic orders and ordering temperatures both at zero and other pressures agree well with experiments including the large increase in the Cur...

This paper presents an optimization strategy based on mathematical programming to solve resource management problems regarding hospitalization of sick patients, considering emergency scenarios, such as those that can occur in a pandemic. is the use efficient tools solving complex which other strategies are not efficient. The modeling epidemiological phenomena useful tool predict direction disea...

AIM To evaluate the ability of structural parameters (as determined by retinal nerve fibre layer (RNFL) measurements obtained with the scanning laser polarimeter (SLP-NFA/GDx)) and functional parameters (as determined by automated perimetry) to discriminate between normal and glaucomatous eyes. METHODS In a case-control study, a total of 91 normal subjects and 94 patients with glaucoma underw...