AbstractVarious nanoparticles have been investigated as novel drug delivery systems, including solid lipid nanoparticles (SLNs). Due to their rapid clearance from systemic circulation, nanoparticles do not provide sustained action in most cases. Different strategies have been employed to overcome this problem. In this direction, the present study introduces erodible in-situ forming gel systems ...

Background: There are various methods to read out responses of a polymer-gel dosimeter, among which the Magnetic Resonance Imaging (MRI) technique is the most common one. Optimizing imaging protocols can have significant effect on the sensitivity and the dose resolution of polymer gel dosimeters. This study has investigated the effects of the number of echoes (NOE) and the echo time spacing (ES...

We have modified one of the most useful methods of protein separation; namely, two dimensional gel electrophoresis (2-DE). This modified version of 2-DE is not only simpler and easier but also faster than all the currently available methods. In this method, isoelectric focusing is carried out in the first dimension using a vertical sodium dodecyl sulfate polyacrylamide gel electrop...

AbstractVarious nanoparticles have been investigated as novel drug delivery systems, including solid lipid nanoparticles (SLNs). Due to their rapid clearance from systemic circulation, nanoparticles do not provide sustained action in most cases. Different strategies have been employed to overcome this problem. In this direction, the present study introduces erodible in-situ forming gel systems ...

Preparation and characterization of thermoresponsive in-situ forming poloxamer hydrogel for controlled release of Nile red-loaded solid lipid nanoparticles. Nanoparticles (NPs) are cleared rapidly from systemic circulation and do not provide sustained action in most cases. To solve this problem, this investigation introduces an erodible in-situ forming gel system as potential vehicles for prolo...

in this investigation, fluor-hydroxyapatite (fha) film was deposited on a titanium substrate by sol-gel method. triethyl phosphite, ammonium fluoride and calcium nitrate in ethanol solutions were used respectively as p, f and ca precursors. typical apatite structures were obtained for all coatings after dipping and subsequent heat treatment at 550, 700 and 800 ºc, the coating layers were invest...