A reaction-diffusion process induced from a micronetwork geometry amplifies changes in the molecular structure of a thin gel film into macroscopic readout patterns. When the gel undergoes a helix-to-coil phase transition, the patterns formed by RD switch from symmetry-broken to symmetric ones. Theoretical analysis explains how the system reconfigures internally in response to mass transfer betw...

An improved method for the preservation of agar gel precipitin lines has been developed.

PAGE Faults and Fallacies in Microbiology. The Fourth Marjory Stephenson Memorial Lecture BY G. S. WIISON . . . . . . . . . . . . . . . . . Transduction of Streptomycin Resistance in Salmonclla typhimurium BY T. WATANABE and M. WAT~VABE . . . . . . . . . . . . . . . . Transduction of Streptomycin Sensitivity hto Resistant Mutants of SalmoncUa typhimurium BY T. WATA-VABE and M. WATANABE . . . . ...

The repton model is a simple model of the “reptation” motion by which DNA diffuses through a gel during electrophoresis. In this paper we show that the model can be mapped onto a system consisting of two types of particles with hard-sphere interactions diffusing on a one-dimensional lattice. Using this mapping we formulate an efficient Monte Carlo algorithm for the model which allows us to simu...

The aim of this study was to compare pentane-1,5-diol and propane-1,2-diol used as absorption enhancers for cutaneously administered terbinafine. Fresh human skin samples were placed in a continuous flow diffusion cell with a gel containing terbinafine on top of the skin. Receptor fluid samples were analysed using high - performance liquid chromatography. The quantity of gel remaining on the sk...

Ion-exchange chromatography was used to isolate a fraction from disrupted gonococci which reacts with sera from patients with gonococcal disease in complement-fixation and gel-diffusion tests. This antigenic fraction was shown to be the same as that previously described as having been isolated by gel filtration. The method reported here has the advantage of greater rapidity of isolation togethe...

A peak parking-moment analysis method was used for the measurement of surface diffusion coefficient (D(s)) in a reversed-phase liquid chromatography (RPLC) system consisting of a C(18)-silica monolithic column and a mixture of methanol and water (70/30, v/v). The D(s) values experimentally measured were analyzed by considering the correlation with corresponding values of molecular diffusivity (...

A double diffusion-in-agar test was used to investigate precipitation reactions of 75 arboviruses. Specific reactions were regularly observed with members of arbovirus groups B, California, Simbu, Turlock, Hart Park, vesicular stomatitis, and several other arboviruses as well as with a member of the Tacaribe group and a herpesvirus. The results demonstrated the feasibility of applying this tech...

immunize rabbits. The rabbit antiserum was absorbed with normal mouse tissues and tested by gel immunodiffusion with a 2nd group of tumors. The latter were pooled to form 3 distinct groups—strong, weak, and negative reactors. The 3 tumor pools were then used to immunize 3 additional groups of rabbits. The rabbit antisera harvested from the secondary groups were absorbed with spleen homogenate...

Pulsed field gradient nuclear magnetic resonance and proton nuclear magnetic resonance relaxometry were used to study the self-diffusion coefficients and molecular dynamics of linear (PEGs) and spherical probes (dendrimers) in native phosphocaseinate suspensions and in a concentrated rennet gel. It was shown that both the size and the shape of the diffusing molecules and the matrix topography a...