نتایج جستجو برای: gene location
تعداد نتایج: 1340004 فیلتر نتایج به سال:
DNA double strand breaks (DSBs) are the most dangerous form of DNA damage and need to be repaired efficiently in order to maintain genomic stability. The kinase ATM becomes activated upon recognition of DSBs and transduces this into cell cycle checkpoint activation and DNA repair. There are two main pathways by which DSBs can be repaired: Non-homologous end joining (NHEJ) and homologous recombi...
The Fumarase Genes of Escherichia coli: Location of the fumB Gene and Discovery of a New Gene (fumC)
Understanding how DNA binding proteins control global gene expression and chromosomal maintenance requires knowledge of the chromosomal locations at which these proteins function in vivo. We developed a microarray method that reveals the genome-wide location of DNA-bound proteins and used this method to monitor binding of gene-specific transcription activators in yeast. A combination of locatio...
At the request of the American Joint Committee on Cancer (AJCC), non-anatomic (non-TNM) classifications were evaluated and important classifications incorporated into staging recommendations for oesophageal cancer in the 7th edition of the Cancer Staging Manual [1]. Cancer location, histopathological cell type and histological grade were demonstrated to enhance cancer staging [2]. Adenocarcinom...
Background: Bax and Bcl-2 are the major members of Bcl-2 family whose play a key role in tumor progression or inhibition of intrinsic apoptotic pathway triggered by mitochondrial dysfunction. Therefore, the balance between pro- and anti-apoptotic members of this family can determine the cellular fate. Methods: In this study, the relative level of mRNA expression of Bax and Bcl-2 genes was deter...
Antibiotic resistance surveys are published widely, citing percentage resistance rates, sometimes for vast transcontinental regions. Such data seem straightforward, but when one drills deeper, great complexity emerges. Rates for methicillin resistance among Staphylococcus aureus from bacteraemias vary from <1% to 50% among European countries, and vary greatly among both hospitals and hospital u...
Recent studies have shown that many proteins that regulate planar polarity in the fly eye are organized into discrete membrane sites which may be crucial for coordinating groups of cells.
In the early 1980s, by determination of Boorola gene (FecB) in Booroola sheep with high ovulation rate, there has been a great interest for identification genes that are responsible prolificacy and their use breeding programs. The mutation occurred Bone morphogenetic protein 15 (BMP15), protein-1B (BMPR-1B) Growth differentiation factor 9 (GDF9) have found to increase rate. Additionally some ot...
This chapter describes the metabolic pathways for Neurospora crassa in the biosynthesis of amino acids, purines, pyrimidines, vitamins, and cofactors, and for glycolysis, the TCA and glyoxylate cycles and the initial stages of the pentose phosphate pathway. For each step in metabolism, the gene or genes within the genome sequence of the species is identified, correlations are made with previous...
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