Investment decision making in the energy sector is a complex process due to inherent long-term uncertainty. This work investigates importance of representing wide range economic and physical sources uncertainty modelling electricity market, both for investment descriptive market modelling. The results demonstrate that difference between deterministic stochastic solution increases non-linearly w...

BACKGROUND AND AIMS Increasing evidence has suggested that hepatocellular carcinoma (HCC) might originate from a distinct subpopulation called cancer stem cells (CSCs), which are responsible for the limited efficacy of conventional therapies. We have previously demonstrated that granulin-epithelin precursor (GEP), a pluripotent growth factor, is upregulated in HCC but not in the adjacent non-tu...

C-X-C motif chemokine receptor 4 (CXCR4) and somatostatin receptors (SSTR) are overexpressed in gastro-entero-pancreatic neuroendocrine tumors (GEP-NET). In this study, we aimed to elucidate the feasibility of non-invasive CXCR4 positron emission tomography/computed tomography (PET/CT) imaging in GEP-NET patients using [68Ga]Pentixafor in comparison to 68Ga-DOTA-D-Phe-Tyr3-octreotide ([68Ga]DOT...

BACKGROUND AND AIM Granulin-epithelin precursor (GEP) has previously been reported to control cancer growth, invasion, chemo-resistance, and served as novel therapeutic target for cancer treatment. However, the nature and characteristics of GEP interacting partner remain unclear. The present study aims to identify and characterize the novel predominant interacting partner of GEP using co-immuno...

In this paper, we study the long-term power generation investment expansion planing problem under uncertainty. We propose a bilevel optimization model that includes an upper-level multistage stochastic expansion planning problem and a collection of lower-level economic dispatch problem. This model seeks for the optimal sizing and siting for both thermal and wind power units to be built to maxim...

* Climate change projections predict an intensifying hydrologic cycle and an increasing frequency of droughts, yet quantitative understanding of the effects on ecosystem carbon exchange remains limited. * Here, the effect of contrasting precipitation and soil moisture dynamics were evaluated on forest carbon exchange using 2 yr of eddy covariance and microclimate data from a 50-yr-old mixed oak...

This paper proposes a novel method for transmission network expansion planning (TNEP) that take into account uncertainties in loads and renewable energy resources. The goal of TNEP is to minimize the expansion cost of candidate lines without any load curtailment. A robust linear optimization algorithm is adopted to minimize the load curtailment with uncertainties considered under feasible expan...

The paper presents a modeling framework to analyze some important issues associated with operation planning of a power system. Major activities involved in operations planning of large integrated power systems are considered simultaneously to ensure optimal utilization of generation and transmission capacity. The model also examines optimal transmission expansion plans vis-aÁ -vis fuel supply i...