Polymorphisms identified in genome-wide association studies of human traits rarely explain more than a small proportion of the heritable variation, and improving this situation within the current paradigm appears daunting. Given a well-validated dynamic model of a complex physiological trait, a substantial part of the underlying genetic variation must manifest as variation in model parameters. ...

Some environmental effects, population genetic parameters, breeding value of Limousin bulls, also phenotypic and trends in the age at first calving (AFC) cows between 1992 2013 were estimated. Data served by Blonde d’Aquitaine Breeders Association, Hungary. The study was extended to three herds 1157 cows. GLM method used for different BLUP animal model estimation parameters values (BV), one-way...

bean root rot caused by plant pathogenic fungus, fusarium solani, is considered one of the most important diseases of bean in the world and in iran. because of economic importance of bean and the lack of information on population diversity of the pathogen in zanjan province, a research was conducted to study phenotypic, genotypic and pathogenicity variation of pathogen isolates and to assess pa...

Quantitative genetic models of evolution rely on the genetic variance-covariance matrix to predict the phenotypic response to selection. Both prospective and retrospective studies of phenotypic evolution across generations rely on assumptions about the constancy of patterns of genetic covariance through time. In the absence of robust theoretical predictions about the stability of genetic covari...

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