Nearly all aspects of human development are influenced by genetic and environmental factors, which conjointly shape development through several gene-environment interplay mechanisms. More recently, researchers have begun to examine the influence of genetic factors on peer and family relationships across the pre-adolescent and adolescent time periods. This article introduces the special issue by...

background: populations of magnaporthe, the causal agent of rice blast disease, are pathotypically and genetically diverse and therefore their interaction with different rice cultivars and also antagonistic microorganisms are very complicated. objectives: the objectives of the present study were to characterize phylogenetic relationships of 114 native  magnaporthe strains, isolated from rice an...

Description The package contains functions that 1) estimates gene-environment interaction between a SNP and a continuous non-genetic attribute by fitting a generalized additive model to case-parent trio data, 2) produces graphical displays of estimated interaction, 3) performs permutation test of gene-environment interaction; 4) simulates informative case-parent trios.

Both nurture (environmental) and nature (genetic factors) play an important role in human disease etiology. Traditionally, these effects have been thought of as independent. This perspective is ill informed for non-mendelian complex disorders which result as an interaction between genetics and environment. To understand health and disease we must study how nature and nurture interact. Recent ad...

Gene-environment (G×E) interaction plays a pivotal role in understanding the genetic basis of complex disease. When environment factors are measured in a continuous scale, one can assess the genetic sensitivity over different environmental conditions on a disease phenotype. Motivated by the increasing awareness of the power of gene set based association analysis over single variant based approa...

Cryptic genetic variation (CGV) refers to genetic variants whose effects are buffered in most conditions but manifest phenotypically upon specific genetic and environmental perturbations. Despite having a central role in adaptation, contribution of CGV to regulation of quantitative traits is unclear. Instead, a relatively simplistic architecture of additive genetic loci is known to regulate phe...

many qtls related to agronomic triats have been registered in soybean (glycine max) by different research groups during the last decade. due to the interaction effects of qtls, environmental and genetic backgrounds on the emergence of qtls and also to confirm the previous results as well as to identify new qtls, further studies are still required. in order to map qtl which control some agronomi...

Over the past three decades, a large number of genetic studies have been aimed at finding genetic variants associated with the risk of asthma, applying various genetic and genomic approaches including linkage analysis, candidate gene polymorphism studies, and genome-wide association studies (GWAS). However, contrary to general expectation, even single nucleotide polymorphisms (SNPs) discovered ...