AIMS To characterise the inheritance of ptosis in one particular pedigree. METHODS The pedigree was analysed clinically and genetically to assess the mode of inheritance and to ascribe a gene locus for the condition. RESULTS Affected members of the pedigree have bilateral symmetrical congenital isolated ptosis, a condition which is linked to genetic markers on the X chromosome in this famil...

the objective of this study was to estimate genetic parameters and to investigate the type of gene action in controlling androgenesis in wheat. two wheat cultivars of grebe and houtman were reciprocally crossed with two synthetic genotypes of do1 and pol and then a complete set of the parents, f1, reciprocal f1 (rf1), f2 and back-cross generations (bc1 and bc2) of each cross were used for anthe...

BACKGROUND The etiogenesis of congenital portosystemic shunt in dogs is not understood. In Irish Wolfhounds, intrahepatic portosystemic shunt (IHPSS) is thought to be hereditary, but the mode of inheritance is unknown. OBJECTIVES To document the genetic background and investigate the potential mode of inheritance of IHPSS in Irish Wolfhounds. ANIMALS Three mature, privately owned, affected ...

Pistacia atlantica is the most important tree species for the economy of many rural areas in west of Iran, but no effort has been made for the genetic improvement of this species. The aim of this investigation was to study the genetic variation and inheritance of early growth traits in P. atlantica. For this purpose, three wild pistachio populations comprising 60 randomly selected adult trees f...

A number of human pathologies have a transmission pattern that does not obey Mendelian segregation rules. This type of heredity is defined as non-Mendelian and is based on mechanisms of transgenerational epigenetic inheritance. Comprehensive information on the molecular mechanisms of it is still lacking. However, recent evidence from distantly related species including Caenorhabditis elegans, D...

An introduction to the workshop and its main aims. (1) To discuss the historical origins of the separation of development and inheritance and their description in genetic terms, and how this shaped the development of research programs within evolutionary biology; (2) To explore the possible implications of alternative conceptualizations of inheritance, and the development-heredity relationship,...

Using a simple simulation model of evolution and learning, this paper provides an evolutionary argument why Lamarckian inheritance the direct transfer of lifetime learning from parent to offspring may be so rare in nature. Lamarckian inheritance allows quicker genetic adaptation to new environmental conditions than non-lamarckian inheritance. While this may be an advantage in the short term, it...

Genomic concepts are based on the assumption that phenotypes arise from the expression of genetic variants. However, the presence of non-Mendelian inheritance patterns provides a direct challenge to this view and suggests an important role for alternative mechanisms of gene regulation and inheritance. Over the past few years, a highly complex and diverse network of noncoding RNAs has been disco...

THIS book is the outcome of a symposium held on 1st and 2nd December 1977, at the Royal College of Physicians of Edinburgh. There is little doubt that genetic factors have become increasingly important in the aetiology of disease, and it has been estimated that some 5 -7%o of the population will suffer from a disorder with a genetic basis. The first five chapters of the book cover basic topics ...

Clinical geneticist tries to identify the etiology, mode of inheritance and the risk that a similar disorder may occur in the affected childs’ siblings. Five different categories are required for classification of the patients' disorder. Single gene mutations account for 6% of the children with congenital anomalies, chromosomal disorders 7.5%, multifactorial inheritance 20%, and disorders with ...