As the number of complete genomes that have been sequenced keeps growing, unknown areas of the protein space are revealed and new horizons open up. Most of this information will be fully appreciated only when the structural information about the encoded proteins becomes available. The goal of structural genomics is to direct large-scale efforts of protein structure determination, so as to incre...

The sequencing of the first genome of a higher plant, Arabidopsis, is progressing at a rapid pace. As we are writing these words, almost one-third of the estimated 100 Mb is available in public databases, and with appropriate funding the complete genome sequence is predicted to be finished by the year 2001. Sequencing programs for other plant genomes such as rice are planned, and with new gener...

Only half a century after the landmark discovery of the double helix structure of DNA, the human genome was sequenced and a new era of biomedical research was ushered in [1]. Parallel advances in comparative genomics, genetics, highthroughput biochemical techniques, and bioinformatics have provided researchers in wealthy nations with a repertoire of tools to analyze the sequence and functions o...

The Functional Genomics and Disease 2003 conference was held at the Hilton Hotel in Prague, the beautiful capital of the Czech Republic, on 14–17 May 2003. This conference provided an ideal forum for European specialists to converge in the geographical centre of Europe to discuss the progress made in, and future prospects for, the important field of genomics in disease, and presented an opportu...

EDITORIAL article Front. Genet., 14 July 2023Sec. Computational Genomics Volume - 2023 | https://doi.org/10.3389/fgene.2023.1252328

Department of Biochemistry, Center for Human Genomics, Center for Diabetes Research, Program in Molecular Genetics and Genomics, Department of Pediatrics, Department of Biostatistical Sciences, Department of Internal Medicine, Section on Nephrology, Department of Internal Medicine, Wake Forest University, Winston Salem, NC Center for Research on Genomics and Global Health, National Human Genome...

Journal: Biochemistry and Cell Biology Manuscript ID bcb-2016-0005.R4 Manuscript Type: Article Date Submitted by the Author: 27-Apr-2016 Complete List of Authors: Duan, Yangmiao; Key Laboratory of Genomics and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences Fang, Hongbo; Beijing Institute of Genomics Chinese Academy of Sciences Keyword: RecQL4, autophagy, mitophag...

Two years ago, NIH's Undiagnosed Diseases Program began delivering genomics to the clinic on an unprecedented scale. Now, with 128 exomes sequenced and 39 rare diseases diagnosed, the program's success is paving the way for widespread personal genomics while pioneering new techniques for reigning in the "tsunami" of genomics data.