Dengue virus serotype 2 (DENV-2) isolates have been implicated in deadly outbreaks of dengue fever (DF) and dengue hemorrhagic fever (DHF) in several regions of the world. Phylogenetic analysis of DENV-2 isolates collected from particular countries has been performed using partial or individual genes but only a few studies have examined complete whole-genome sequences collected worldwide. Herei...

lanthanide(iii) chloro complexes of 4[n-(4’-hydroxy-3’-methoxybenzalidene) amino] antipyrine semicarbazone (hmbaaps) (i) and 4[n-(3’,4’,5’-trimethoxybenzalidene) amino] antipyrine semicarbazone (tmbaaps) (ii) with the general composition lncl3.2l (ln = la, pr, nd, sm, gd, tb, dy or ho; l = hmbaaps or tmbaaps) are reported. all the complexes were synthesized in ethanolic medium and refluxed the ...

We report here a comparative study of the anti-hepatitis C virus (HCV) activities of selected (i) nucleoside polymerase, (ii) nonnucleoside polymerase, (iii) alpha,gamma-diketo acid polymerase, (iv) NS3 protease, and (v) helicase inhibitors, as well as (vi) cyclophilin binding molecules and (vii) alpha 2b interferon in four different HCV genotype 1b replicon systems.

An Oropouche virus strain was isolated from a novel host (Callithrix sp.) in Arinos, Minas Gerais State, southeastern Brazil. The virus was identified by complement fixation test and confirmed by reverse transcription-polymerase chain reaction. Phylogenetic analysis identified this strain as a genotype III isolate previously recognized only in Panama.

BACKGROUND AND PURPOSE Pretherapeutic determination of tumor grade and genotype in grade II and III oligodendroglial tumors is clinically important but is still challenging. Tumor grade and 1p/19q status are currently the 2 most important factors in therapeutic decision making for patients with these tumors. Histopathology and cMRI studies are still limited in some cases. In the present study, ...

PURPOSE Aromatase, encoded by the CYP19 gene, catalyzes the final step of the conversion of androgens to estrogens. Given the critical role of CYP19 in estrogen synthesis, the potential influence of CYP19 rs4646 polymorphism on breast cancer survival, deserves further study. METHODS Genotyping for CYP19 rs4646 variants was performed on 406 Chinese women with stage I-II and operable stage III ...

background: the protozoan parasite toxoplasma gondii can infect any warm blooded nucleated cells. one of the ways for human infection is ingestion of oocysts directly from soil or via infected fruits or vegetables. to survey the potential role of t. gondii oocyst in soil samples, the present study was conducted in tehran city, iran. methods: a total of 150 soil samples were collected around rub...

Currently, three genotypes of hepatitis delta virus (HDV) are described. The most common, genotype I, has a worldwide distribution; in contrast, genotype II has been found previously only in Japan and Taiwan, while genotype III is found exclusively in South America. Considering the high prevalence of HDV in Northern Siberia (Russia), restriction fragment length polymorphism (RFLP) was used to a...

BACKGROUND AND AIMS Recently, several genome-wide association studies have revealed that single nucleotide polymorphisms (SNPs) in proximity to IL28B predict spontaneous clearance of HCV infection as well as outcome following peginterferon and ribavirin therapy among HCV genotype 1 infected patients. The present study aimed to evaluate the impact of IL28B SNP variability on liver histology in t...