Acalypha indica (Indian Nettle in English, Kuppaimeni Tamil, Kuppameniya Sinhala) leaves are locally used as herbal remedy. It can induce hemolysis and methemoglobinemia a Glucose-6-Phosphate Dehydrogenase (G6PD) deficient person. Here we report 46-year-old-male was presented with following ingestion. Later, he found to have G6PD deficiency. He completely recovered supportive treatment.