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Atopic dermatitis (AD) is characterized by skin inflammation, barrier dysfunction and chronic pruritus. In this review, recent advances in the pathogenesis of AD are summarized. Clinical efficacy of the anti-IL-4 receptor antibody dupilumab implies that type 2 cytokines IL-4 and IL-13 have pivotal roles in atopic inflammation. The expression of IL-4 and IL-13 as well as type 2 chemokines such a...
Background: Very recently, Eric Topol, a physician-scientist, introduced his “deep medicine” theory in 2019. This theory has been originated from the last two decades advancements of systems medicine and digital medicine, science and technology convergence in biological fields and formation of the precision medicine. The transcendent medicine theory that has been derived from Sadr ad-Din Shiraz...
This article ties to survey the evolution trend of development theories to demonstrate that such theories have undergone impressive transformation within the recent 60 years. The first generation of the thinkers paid attention to the macroeconomic neo-classical models and the second generation of them took various factors ranging from market mechanisms to human capital. However, the governance ...
Although there are proposals in the literature for authoring mulsemedia ( mul tiple xmlns:xlink="http://www.w3.org/1999/xlink">se nsorial xmlns:xlink="http://www.w3.org/1999/xlink">media ) applications with 2D content, no suitable solutions when it comes to 360° content. Moreover, littl...
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