Diabetes mellitus (DM) is a chronic progressive metabolic disorder characterized by hyperglycemia mainly due to absolute (Type 1 DM) or relative (Type 2 DM) deficiency of insulin hormone. World Health Organization estimates that more than 346 million people worldwide have DM. This number is likely to more than double by 2030 without any intervention. The needs of diabetic patients are not only ...

BACKGROUND With the increasing prevalence of diabetes in patients aged over 75, the task of ensuring a good quality of life became even greater. This study aimed to evaluate quality of life of the very elderly (≥75 years) type 2 diabetic primary care patient, in an urban family practice setting. METHODS A cross sectional study was conducted. Quality of life (QoL) was assessed with the Portugu...

conclusions it seems that rj does not appear to have significant immediate effects on glycemic factors in patients with type 2 diabetes. however, further studies with larger sample sizes and different doses of rj are needed to achieve more precise results. background type 2 diabetes is the fourth major public health problem worldwide. royal jelly (rj) insulin-like activity and blood glucose mod...

The Joslin 50-Year Medalist Study T he Joslin Gold Medalists comprise 351 U.S. residents who have survived with type 1 diabetes for .50 years. A high proportion of Medalists remain free from proliferative diabetic reti-nopathy (PDR) (42.6%), nephropathy (86.9%), neuropathy (39.4%), or cardio-vascular disease (51.5%). Current and longitudinal (the past 15 years) glycemic control were unrelated t...

Glucokinase (GCK) plays a key role in glucose homeostasis. Gestational diabetes mellitus increases the risk of gestational complications in pregnant women and fetuses. We screened for mutations in coding and flanking regions of the GCK gene in pregnant women with or without gestational diabetes in a Brazilian population. A sample of 200 pregnant women classified as healthy (control, N = 1...