نتایج جستجو برای: gp63
تعداد نتایج: 204 فیلتر نتایج به سال:
Membrane glycoconjugates on the Leishmania parasites, notably leishmanolysin and lipophosphoglycan, have been implicated in attachment and invasion of host macrophages. However, the function of parasite surface Ag 2 (PSA-2) and membrane proteophosphoglycan (PPG) has not been elucidated. In this study we demonstrate that native and recombinant Leishmania infantum PSA-2, which consists predominan...
BACKGROUND Vaccines that activate strong specific Th1-predominant immune responses are critically needed for many intracellular pathogens, including Leishmania. The requirement for sustained and efficient vaccination against leishmaniasis is to formulate the best combination of immunopotentiating adjuvant with the stable antigen (Ag) delivery system. The aim of the present study is to evaluate ...
Background: Different methods have been used for characterization of Leishmania promastigotes. Monoclonal antibodies are useful in characterization of Leishmania spp . both amastogotes and promastigotes. Objective: Comparing the characterization of Leishmania spp. promastigotes with immunoperoxidase test (Avidin-Biotin) techniques and an indirect immunofluorescent assay (IFA). Methods: Ap...
انگلهای لیشمانیا تک یاختههایی از جنس لیشمانیا و عضوی از خانواده تریپانوزوماتیده هستند که باعث ایجاد انواع لیشمانیوز میشوند. عوامل مؤثر در بیماریزایی انگلهای لیشمانیا عبارتند از عوامل مربوط به انگل، پشه ناقل، میزبان مهره دار و محیط. عوامل مربوط به انگل شامل فاکتورهای ویرولانس موجود در انگلهای لیشمانیا است که مهمترین آنها LPG و GP63 میباشند. این عوامل از چندین سال پیش مورد توجه محققین به ...
BACKGROUND Chagas disease is a debilitating often fatal disease resulting from infection by the protozoan parasite Trypanosoma cruzi. Chagas disease is endemic in 21 countries of the Americas, and it is an emerging disease in other countries as a result of migration. Given the chronic nature of the infection where intracellular parasites persist for years, the diagnosis of T. cruzi by direct de...
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