UNLABELLED The aim of this study was to evaluate the effects of grape juice on colon carcinogenesis induced by azoxymethane (AOM) and expression of NF-kB, iNOS and TNF- α. METHODS Forty male Wistar rats were divided into 7 groups: G1, control; G2, 15 mg/kg AOM; G3, 1% grape juice 2 weeks before AOM; G4, 2% grape juice 2 weeks before AOM; G5, 1% grape juice 4 weeks after AOM; G6, 2% grape juic...

UNLABELLED Grape juice processing by-products, grape seed and pomace are a rich source of procyanidins, compounds that may afford protection against chronic disease. This study was undertaken to identify optimal extrusion conditions to enhance the contents of monomers and dimers at the expense of large molecular weight procyanidin oligomers and polymers in grape seed and pomace. Extrusion varia...

Prediabetes is a condition affecting 35% of US adults and about 50% of US adults age 65+. Foods rich in polyphenols, including flavanols and other flavonoids, have been studied for their putative beneficial effects on many different health conditions including type 2 diabetes mellitus and prediabetes. Studies have shown that some flavanols increase glucagon-like peptide 1 (GLP-1) secretion. GLP...

(-)-Rotundone is a potent odorant molecule with a characteristic spicy aroma existing in various plants including grapevines (Vitis vinifera). It is considered to be a significant compound in wines and grapes because of its low sensory threshold and aroma properties. (-)-Rotundone was first identified in red wine made from the grape cultivar Syrah and here we report the identification of VvSTO2...

Polyphenols in grape and wine have been suggested to contribute to the cardiovascular health benefits of the Mediterranean lifestyle. The reported effects of grape products on blood pressure (BP) remain, however, equivocal. In a double-blind placebo controlled crossover study, the effect of two grape extracts on BP and vascular function was assessed in 60 untreated, mildly hypertensive subjects...

Objectives: Cetuximab is an anticancerous drug which causes oral mucositis as a major side effect. Oral mucositis can be reduced by the effect of grape seed extract which modulates the inflammatory pathways. Our aim is to evaluate the effect of Grape seed extract and Cetuximab drug on mucositis and bacterial infection in tongue mucosa of experimental rats. Design: 24 rats were housed in the ani...

INTRODUCTION Streptococcus mutans has been implicated as primary microorganisms which cause dental caries in humans. There has been an increased interest in the therapeutic properties of some medicinal plants and natural compounds which have demonstrated antibacterial activities. Grape is one of the plants of this group which contains tannin and polyphenolic compound. AIM To evaluate and comp...

Title of Document: ANTIOXIDANT AND ANTIPROLIFERATIVE PROPERTIES OF SELECTED GRAPE SEED EXTRACTS Raquel Zorah Bloom, Master of Science, 2009 Directed By: Associate Professor Dr. Liangli Yu Nutrition and Food Science This study examined chardonnay, muscadine, concord, and ruby red grape seed oil and flour extracts for antioxidant and anti-proliferative properties. The extracts were tested for tot...

Background Persistent psychological stress often leads to anxiety disorders and depression. Benzodiazepines and selective serotonin reuptake inhibitors are popular treatment options but have limited efficacy, supporting the need for alternative treatment. Based on our recent preclinical work suggesting a causal link between neurobehavioral deficits and elevated oxidative stress, we hypothesized...

rashe grape cultivar grows in kurdistan province in rain fed conditions. microclimate conditions have a great effect on grape berry quality. information about changes in grape berry composition in the relation to climate changes is limited. in order to measure the effects of slope and altitude on some grape berry chemical composition, a study was conducted on grape cv. ‘rasheh’ in university of...