Objective(s):Diabetes plays an important role in the induction of the liver injury. Grape seed proanthocyanidin (GSP) have a wide range of medicinal properties against oxidative stress. In this study we evaluated antioxidant effects of GSP on liver in streptozotocin-induced diabetic rats. Materials and Methods: Thirty male Sprague–Dawley rats were divided into three groups: control, untreated d...

Background: Infertility is a disease of the reproductive system that inhibits the ability of a couple to have a Baby. Cyclosporine A (CsA) is a powerful immunosuppressant drug most widely used in management of organ transplantation and autoimmune diseases. The drug has adverse side effects such, hirsutism, and gynecomastia. Hawthorn is one of the oldest herbal medicines that are widely used in ...

the effect of different solvent systems on the extraction of antioxidant and anti radical agents of grape seed was studied. for this purpose 6 different solvent systems with similar polarity and different selectivity were used to prepare grape seed extract. extraction efficiency, reducing activity, radical scavenging property and the effect of each extract on the increase of thermal resistance ...

This study was carried out to evaluate the effect of heating and physical conditions of grape seeds on the antioxidant activity of their extracts. Two forms of grape seeds, whole and powdered forms, were heated at four different temperatures 50, 100, 150 and 200 C. After heating, grape seeds were extracted with 70% ethanol (0.1 g grape seed/10 mL of 70% ethanol), and total phenol contents (TPC)...

As we reported earlier, Muscat Bailey A (MBA) wine has very low proanthocyanidin (PA) content compared with Cabernet Sauvignon (CS) and Merlot wines. Whereas PA concentration in CS was maintained at the maximum level during maceration, that in MBA reached a maximum approximately four days after maceration and drastically decreased thereafter. In this study, the model wine extraction profiles of...