The efficacy of Andrographis paniculata (AP) extract was studied on atrazine induced hepatic damage in rats. Ethanolic extract of AP (150mg/kg body weight) was found to protect the male wistar rats from hepato toxic action of atrazine as evidence by significant reduction in the level of lipid peroxidation and increased the antioxidant defense system activity in the atrazine intoxicated rats. Ho...

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Andrographis paniculata (Burm. F.) Wall. Ex Nees (Family: Acanthaceae), commonly known as Kalmegh or ‘‘King of Bitters”, is one of the many traditionally known medicinal plants listed in WHO herbal Monograph [1]. It is a rich natural source of bioactive labdane diterpinoids like andrographolide, neoandrographolide, isoandrographanolide, andrograpanin, etc. Amongst them andrographolide is quanti...

Six species of lesser known edible fruits from Western Ghats of India were analysed for their anthocyanin, ascorbic acid, total phenolics and flavonoid levels and their antioxidant activities using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method. The data obtained shown the anthocyanin, ascorbic acid, total phenolics and flavonoid levels were significantly higher in the methanol extract of Maho...

A new α-pyrone, 6R-[5R,6S-diacetyloxy-1Z,3E-heptadienyl]-5,6-dihydro-2H-pyran-2one (1), along with six known compounds including an α-pyrone, flavones and terpenes was isolated from the aerial parts of Neohyptis paniculata. The structure of 1 was established unambiguously by MS and a series of 1D and 2D-NMR spectroscopic analyses. The antibacterial activity of the compounds (1-7) was investigat...

The coumarin ring system in the title compound, C(15)H(18)O(5) [IUPAC name: 8-(2,3-dihydr-oxy-3-methyl-butyl)-7-meth-oxy-2H-1-benzopyran-2-one], isolated from Muraya paniculata, is planar (r.m.s. deviation 0.017 Å). In the crystal, the two hydr-oxy groups are involved in O-H⋯O hydrogen bonding with adjacent mol-ecules, forming a sheet structure.

Ethanolic extracts of eight medicinal plants commonly used in folk medicine were tested for their antibacterial activity against four Gram positive strains (Bacillus subtilis, Staphylococcus aureus, Staphylococcus epidermidis and, Streptococcus pneumoniae) and six Gram negative strains (Escherichia coli, Proteus vulgaris, Proteus mirabilis. Salmonella typhi para A, Salmonella typhi para B and S...