We present Chandra observations of black hole X-ray novae V404 Cyg, A0620–00, GRO J1655–40 and XTE J1550–564 in quiescence. Their quiescent spectra can be well fitted by a power-law model with number slope α∼ 2. While a coronal (Raymond-Smith) model is also a statistically acceptable representation of the spectra, the best fit temperatures of these models is ∼ 5 times higher than that seen in a...

Toll-like receptor 4 (TLR4) activation mediates renal injury in regional ischemia and reperfusion (I/R) models generated by clamping renal pedicles. However, it remains unclear whether TLR4 is causal in the kidney injury following global I/R induced by cardiac arrest (CA) and cardiopulmonary resuscitation (CPR). The present study used wild‑type (C3H/HeN) and TLR4‑mutant (C3H/HeJ) mice to produc...

INTRODUCTION Nowadays it is thought that the main cause of premature birth is subclinical infection. However, none of the currently used methods provide effective prevention to preterm labor. The aim of the study was to determine the concentration of selected chemokines in sera of patients with premature birth without clinical signs of infection (n = 62), threatened preterm labor (n = 47), and ...

Recently, green reduction of graphene oxide (GRO) using various natural materials, including plant extracts, has drawn significant attention among the scientific community. These methods are sustainable, low cost, and are more environmentally friendly than other standard methods of reduction. Herein, we report a facile and eco-friendly method for the bioreduction of GRO using Salvadora persica ...

During development, neuronal identity is determined by a combination of numerous transcription factors. However, the mechanisms of synergistic action of these factors in transcriptional regulation and subsequent cell fate specification are largely unknown. In this study, we identified a novel gene, Corl1, encoding a nuclear protein with homology to the Ski oncoprotein. Corl1 was highly selectiv...

Исследованы новые магнитные нанокомпозиты (МНК) оксид графена (GrO)/магнетит (Fe 3 O 4 ) + кобальтовый феррит (CoFe 2 различных концентраций синтезированные механохимическим методом, представляющим собой процесс механического измельчения в шаровой мельнице водной среде оксида и предварительно синтезированных порошков магнетита феррита кобальта. Были получены исследованы МНК GrO/Fe CoFe полученн...

We present observational evidence for “propeller” effects in two X-ray pulsars, GX 114 and GRO J1744228. Both sources were monitored regularly by the Rossi X-ray Timing Explorer (RXTE) throughout a decay period in the X-ray brightness. Quite remarkably, strong X-ray pulsation became unmeasurable when total X-ray flux had dropped below a certain threshold. Such a phenomenon is a clear indication...

Background Tumor Necrosis Factor-α(TNF- α) and Interleukin(IL-1) are well-known in the induction of senescence chondrocytes play an important role pathogenesis Osteoarthritis (OA). However, targeting these pathways has not yielded promising results. The chemokines IL-8(CXCL8) Gro-α(CXCL1), as well CXCR1/2 pathways, known to mediate inflammation apoptosis. precise OA is unknown. We hypothesize t...

We analyze RXTE/PCA observations of the black hole candidate and galactic superluminal source GRO J1655–40 during its recent outburst. We show that during its decay to quiescence, GRO J1655–40 goes through the high, intermediate, and low state (and that at the beginning of its decay it might have even shown signatures of a very high state), just like other black hole candidates. This is the fir...