We have investigated the role of IL-6 in the initiation and progression of mouse mammary gland involution in IL-6-null mice. This study was based on the hypothesis that IL-6 is the activating cytokine for signal transducer and activator of transcription 3 (Stat), the transcription factor whose presence is required for controlled mammary gland involution. We now show that expression of IL-6 is l...

This research was conducted to find out the reproductive disorders of postpartum and effectiveness its treatment in various nations beef cattle. A total 30 cattle raised groups D.I.Y. area used as samples. Cows are divided into three namely control group, iodine povidone infusion antibiotic group. First, second, third months performed clinical examination, blood collection, rectovaginal examina...

We define an invariant of torsors under adjoint linear algebraic groups of type Cn—equivalently, central simple algebras of degree 2n with symplectic involution—for n divisible by 4 that takes values in H(k, μ2). The invariant is distinct from the few known examples of cohomological invariants of torsors under adjoint groups. We also prove that the invariant detects whether a central simple alg...

In this paper we investigate the left cell representations of the Iwahori{Hecke algebras associated to a nite Coxeter group W. Our main result shows that T w0 , where w 0 is the element of longest length in W , acts essentially as an involution upon the canonical bases of a cell representation. We describe some properties of this involution, use it to further describe the left cells, and nally ...

An anti-holomorphic multiplication by the integers Od of a quadratic imaginary number field, on a principally polarized complex abelian variety AC is an action of Od on AC such that the purely imaginary elements act in an anti-holomorphic manner. The coarse moduli space XR of such A (with appropriate level structure) is shown to consist of finitely many isomorphic connected components, each of ...

One of the most striking changes during mammal aging is a progressive involution of the thymus, associated with an increase in susceptibility to infections, autoimmune diseases and cancer. In order to delay age-related processes, we have developed mitochondria-targeted antioxidant plastoquinonyl decyltriphenyl phosphonium (SkQ1). Here we report that, at low doses, SkQ1 (250 nmol/kg per day) inh...

Let G be a complex semisimple Lie group and τ a complex an-tilinear involution that commutes with the Cartan involution. If H denotes the connected subgroup of τ-fixed points in G, and K is maximally compact, each H-orbit in G/K can be equipped with a Poisson structure as described by Evens and Lu. We consider symplectic leaves of certain such H-orbits and show that an application of the symple...

Let G be a reductive group in the Harish-Chandra class e.g. a connected semisimple Lie group with finite center, or the group of real points of a connected reductive algebraic group defined over R. Let σ be an involution of the Lie group G, H an open subgroup of the subgroup of fixed points of σ. One decomposes the elements of L(G/H) with the help of joint eigenfunctions under the algebra of le...

Involution is the process of post-lactational mammary gland regression to quiescence and it involves secretory epithelial cell death, stroma remodeling and gland repopulation by adipocytes. Though reportedly accompanying apoptosis, the role of autophagy in involution has not yet been determined. We now report that autophagy-related (ATG) proteins mediate dead cell clearance and suppress inflamm...

Recent pregnancy correlates with decreased survival for breast cancer patients compared with non-pregnancy-associated breast cancer. We hypothesize that postpartum mammary involution induces metastasis through wound-healing programs known to promote cancer. It is unknown whether alternatively activated M2 macrophages, immune cells important in wound-healing and experimental tumorigenesis that a...