Plateletrich rich fibrin (PRF) is an autologous healing biomaterial, which incorporates a matrix of autologous fibrin, leukocytes, platelets and growth factors, harvested from a simple blood sample. Various growth factors present in PRF are well-known source of cytokines, usable for clinical applications. Grade II furcation lesion is essentially a cul-de-sac with a definite horizontal component...

conclusions the results of this study showed that the meticulous microsurgical nerve repair, which was performed using the vein tubulization induced significantly better sciatic nerve regeneration. however, the addition of bone marrow mesenchymal stem cell to vein conduit failed to promote any significant changes in regeneration outcome. results all animals tolerated the surgical procedures and...

considering the importance of bone augmentation prior to implant placement in order to obtain adequate bone quality and quantity, many studies have been conducted to evaluate different techniques and materials regarding new bone formation. in this study, we investigated the bone healing capacity of two different materials deproteinized bovine bone mineral (dbbm with the trade name of bio-oss) a...

objectives: the aim of this study was to histologically compare the regenerative properties of two allografts manufactured by two iranian companies. materials and methods: in this study, four 8-mm defects were produced in the calvaria of 12 rabbits. in three defects, three types of allografts namely itb, cenobone and grafton were placed and one defect served as control. samples were prepared an...

The objective of this case report is to introduce a customized CAD/CAM freeze-dried bone allograft (FDBA) block for its use in Guided Bone Regeneration (GBR) procedures for severely deficient maxillary bones. Additionally, a special newly developed remote incision technique is presented to avoid wound dehiscence. The results show optimal integration behavior of the FDBA block after six months a...

INTRODUCTION The purpose of this study was to determine factors and clinical situations that influence an endodontist's decision to use guided tissue regeneration (GTR) techniques during endodontic root-end surgery. METHODS An invitation to participate in a web-based survey was e-mailed to 3,750 members of the American Association of Endodontists. Data were collected from 1,129 participants, ...

background: guided tissue regeneration (gtr) allows mesenchymal cells to repopulate the defects. however, there is limited information regarding the effi cacy of different membranes. the present study was designed to histologically and histomorphometrically compare three collagen membranes in regenerative treatment of dehiscence defects in dogs. materials and methods: this 8 weeks experimental ...

Calcifying epithelial odontogenic tumor is a benign neoplasm, but its local destructive potential may lead to the formation of major bone defects. Microscopically, there are some histological variants. Among them, we highlight the clear cell variant due to its more aggressive behavior and a higher incidence of relapse. In this context, it is pertinent to describe the clear cell variant of calci...

Guided bone regeneration has become more predictable due to advances in material sciences. Nevertheless, vertical ridge augmentation (VRA) remains a potential challenge due to the complexity of soft tissue management. This becomes more complicated in the posterior atrophic mandible due to limited access and poorer blood supply. As such, a number of critical elements must be taken into considera...