Research objective: To characterize and to discuss corporate social investment focused on territorial development in Brazil.
 Theoretical framework: Corporate philanthropy community relations.
 Methodology: Narrative approach based a two-fold data collection strategy: semi-structured interviews focus group.
 Results: Three main narratives make sense of the role fostering developm...

BACKGROUND Variance in microarray studies has been widely discussed as a critical topic on the identification of differentially expressed genes; however, few studies have addressed the influence of estimating variance. METHODOLOGY/PRINCIPAL FINDINGS To break intra- and inter-individual variance in clinical studies down to three levels--technical, anatomic, and individual--we designed experime...

This paper describes XRCE’s participation in Large Scale Visual Concept Detection and Annotation Task [16] and Photo Retrieval Task [17] of ImageCLEF 2009. Those tasks both use a new collection which is different and which is much larger than the ones used in past sessions. Moreover, new kinds of challenge to tackle were designed such as new categories to detect or new types of topic to deal wi...

This article contributes to the symposium on Meer’s The Cruel Optimism of Racial Justice. I highlight contributions ongoing debates over fragility racial progress and how white supremacist policy ideology have become normalized. During a moment rising global nationalist movements maintaining realist perspective about is imperative. However, realism depth power racist structures does not mean ab...

With the rise of the Internet, there has been increased interest in the use of computer models to study the dynamics of communication networks. An important aspect of this trend has been the study of dramatic, but relatively infrequent, events that result in abrupt and often catastrophic changes in network state. In the research literature, such catastrophic events have been commonly referred t...

Entanglement and knots occur across all aspects of the physical world. Despite the common belief that knots are too complicated for incorporation into proteins, knots have been identified in the native fold of a growing number of proteins. The discovery of proteins with this unique backbone characteristic has challenged the preconceptions about the complexity of biological structures, as well a...

Keratan sulfate (KS) represents an important family of glycosaminoglycans that are critical in diverse physiological processes. Recently, accumulating evidence has provided a wealth of information on the bioactivity of KS, which established it as an attractive candidate for drug development. However, although KS has been widely explored, less attention has been given to its effect on gut microb...

in dealing with uninvited guests as natural propositions and propositions that are based on primary essential predication, the term “predication” has undergone some semantic changes; according to the elements of “unity” and “difference” three periods may be distinguished: (1) the period in which “what causes the unity” is external and “what causes the difference” is in the mind, (2) the period ...

The authors show by illustration that procedures used to validate the reliability of single-concentration high-throughput screens such as the signal window and Z' factor do not ensure sufficient reliability in potency estimates from concentration response assays. They develop the minimum significant ratio as a statistical parameter to characterize the fold change between 2 compounds run in the ...

In this work we present a probabilistic model to estimate summaries of Affymetrix GeneChip probe level data. Comparisons with two different models were made both on a publicly available dataset and on a study performed in our laboratory, showing that our model performs better for consistency of fold change.