The zebrafish is becoming an increasingly popular model system for both automated drug discovery and investigating hypercholesterolemia. Here we combine these aspects and for the first time develop an automated high-content confocal assay for treatments of hypercholesterolemia. We also create two algorithms for automated analysis of cardiodynamic data acquired by high-speed confocal microscopy....

ABSTRACT First Person is a series of interviews with the first authors selection papers published in Journal Cell Science, helping researchers promote themselves alongside their papers. Anchi Chann author on ‘ Scribble and E-cadherin cooperate to control symmetric daughter cell positioning by multiple mechanisms’, JCS. conducted research described this article while PhD student Sarah Russell's ...

Abstract The method and technology were developed to study the influence of an average diameter, mass rolling friction hawthorn fruits on moisture content during drying process. It was established that smoothed (Crataegus oxyacantha L.) have a large unevenness in diameters 11 mm - 21 weight 1.3 g up 4.2 g. diameter decreases from 16 12.5 with decrease 74.9 14%; coefficient surface working chamb...

Objective: To substantiate the possibility of using polarimetry to control quality tinctures as an additional pharmacopoeial method. Methods: The polarimetric method (POL-1/2, Atago, Japan, measurement accuracy of±0.002 °) was used measure optical activity (α motherwort, valerian and hawthorn tinctures. dynamic light scattering (DLS; Zetasizer Nano ZS, Malvern, UK) assess stability alcoholic aq...