The direct coupling of in-tube solid-phase microextraction (in-tube SPME) with microcolumn liquid chromatography (micro-LC) has been investigated for the analysis of antidepressants in human urine. The use of in-tube SPME has been clearly shown to be advantageous for the on-line coupling of the SPME method, as the sample pretreatment technique, with micro-LC as the separation technique. This is...

Environmental and health aspects of road materials have been discussed for a long time, mostly regarding bitumen and bitumen fumes. However, just a few studies on other types of road materials have been reported. In this doctoral study, two types of materials, asphalt release agents and bituminous sealants, were investigated with regard to chemical characterization and emission profiles. Beside...

Liqueur d’expedition (dosage) is a final sugar addition made to sparkling wine which determines the sweetness and balance of finished product. In present study, influence dosage composition on Maillard reaction-associated products precursors in traditional method (bottle-fermented) wines was evaluated over 18-months storage climate-controlled cellar conditions (14 °C, 70 % relative humidity). E...

The small white apricot is a juicy, delicious fruit with short shelf life. Slight fermentation can significantly promote the flavors and nutrient value of juice. This study used high-performance liquid chromatography (HPLC) headspace solid-phase microextraction combined gas chromatography–mass spectrometry (HS-SPME-GC-MS) to examine physicochemical properties, nutritive flavor substances juice ...

A reliable and sensitive method for simultaneous determination of bisphenol A (BPA) and bisphenol F (BPF) in canned food by gas chromatography-mass spectrometry (GC/MS) is described after extraction and pre-concentration by a new solid-phase microextraction (SPME) adsorbent. The potential of single-walled carbon nanotubes (SWCNTs) as SPME adsorbent for the pre-concentration of environmental con...

An automated extraction and determination method for the gas chromatography (GC)-mass spectrometry (MS) analysis of amphetamine-related drugs in human urine is developed using headspace solid-phase microextraction (SPME) and in-matrix derivatization. A urine sample (0.5 mL, potassium carbonate (5 M, 1.0 mL), sodium chloride (0.5 g), and ethylchloroformate (20 microL) are put in a sample vial. A...

Manual solid-phase microextraction (SPME) coupled with gas chromatography-mass spectrometry is investigated as a possible alternative for the determination of petroleum hydrocarbons in soils. Spiked onto an agricultural soil is a commercial diesel fuel (DF) with the following composition by weight: 12% linear alkanes, 52% saturated hydrocarbons (branched and cyclic), 21% alkylated aromatic hydr...

To investigate the differences in volatile compounds of plum fruit samples from different cultivars, ‘Fengtang’ plum, ‘Kongxin’ and ‘Cuihong’ fruits were analyzed using headspace solid-phase microextraction–gas chromatography–mass spectrometry (HS-SPME-GC-MS). The results demonstrated that a total 938 identified three fruits, including 200 terpenoids, 171 esters, 116 heterocyclic compounds, 89 ...

A simple method for the analysis of nereistoxin and its metabolites in human serum using headspace solid-phase microextraction (SPME) and gas chromatography-mass spectrometry (GC-MS) is developed. A vial containing a serum sample, 5M sodium hydroxide, and benzylacetone (internal standard) is heated to 70 degrees C, and an SPME fiber is exposed for 30 min in the headspace of the vial. The compou...

Breast cancer (BC) remains the most prevalent oncologic pathology in women, causing huge psychological, economic and social impacts on our society. Currently, the available diagnostic tools have limited sensitivity and specificity. Metabolome analysis has emerged as a powerful tool for obtaining information about the biological processes that occur in organisms, and is a useful platform for dis...