OBJECTIVES/HYPOTHESIS To compare changes in hearing in patients with SLC26A4 during early and late childhood. STUDY DESIGN Retrospective chart review. METHODS A total of 102 patients with biallelic SLC26A4 mutations visited the tertiary referral otolaryngology department between March 2005 and February 2015. Newborn hearing screening tests had been performed on 22 of these patients. We anal...

OBJECTIVE To estimate the sensitivity and specificity of pure-tone audiometry hearing screening in the primary care setting. DESIGN Prospective cohort study. SETTING Eight academic and private pediatric practices. PARTICIPANTS A subset of children from a convenience sample of 1061 children between 3 and 19 years of age were screened for hearing loss using pure-tone audiometry. Interventio...

Objective—To compare the cost eVectiveness of various strategies for neonatal hearing screening by estimating the cost per hearing impaired child detected. Design—Cost analyses with a simulation model, including a multivariate sensitivity analysis. Comparisons of the cost per child detected were made for: screening method (automated auditory brainstem response or otoacoustic emissions); number ...

BACKGROUND The mitochondrial m.1555A>G mutation is associated with a high rate of permanent hearing loss, if aminoglycosides are given. Preterm infants have an increased risk of permanent hearing loss and are frequently treated with aminoglycoside antibiotics. METHODS We genotyped preterm infants with a birth weight below 1500 grams who were prospectively enrolled in a large cohort study for ...

The importance of early identification and habilitation of hearing loss for improved access to auditory stimuli and for positive prognosis of speech and language is well established in the literature (American Speech-Language-Hearing Association [ASHA] 2004; Hyde 2005; Joint Commission on Infant Hearing [JCIH] 2007; Kennedy, McCann, Campbell, Kimm and Thornton 2005; Yoshinaga-Itano and Gravel 2...

Hearing loss is one of the common congenital problems among neonates [1]. The prevalence of significant hearing loss ranges from 1.2 per 1,000 healthy newborn infants and 2 to 5% in high-risk newborns [2,3]. Nearly 50% of congenital hearing loss is due to genetic defects [1]. About 50% of hearing defects can be detected in a selective screening based exclusively on hearing risk criteria [1]. Ea...

Background and Objective: Early detection of neonatal hearing disorders is a suitable measure of speech and behavioral development. The aim of this study was to determine the prevalence of hearing disorder in high-risk neonates treated in a neonatal intensive care unit (NICU).  Materials and Methods: This descriptive study was performed on 150 neonates treated in the NICU of Besat Hospital in ...

The incidence of sensorineural hearing loss among infants in the neonatal intensive unit (NICU) is higher than in normal infants. This study determined the rate of hearing loss in healthy newborns and in NICU patients before hospital discharge at a single institution in the Eastern region of the United Arab Emirates; 96.5% of all eligible infants were screened. Hearing deficit was diagnosed in ...

introduction: according to world health organization (who) 2001 statistics, hearing disorders are the most common congenital disease, and the incidence rate among high-risk newborns is as much as ten times as high as that in healthy neonates. however, 78% of screening test failures are well-baby nursery babies. the joint committee on infants’ hearing (jcih) has emphasized the importance of earl...

BACKGROUND This review was commissioned because of the increasing doubt about the ability of existing screening programmes (mainly the health visitor distraction test (HVDT) at 7-8 months) to identify children with congenital hearing impairment, and technological advances which have made neonatal hearing screening an alternative option. OBJECTIVES To review the available literature on the scr...