OBJECTIVE To demonstrate the magnitude of pediatric heart disease problem in Madina, current situation of heart service, obstacles and future expectations. METHODS We conducted this cross sectional study in Madina Maternity and Children Hospital, Madina, Kingdom of Saudi Arabia from January 2007 to June 2008. The study was approved by the Ethical Committee. A computer based program was establ...

BACKGROUND Congenital heart defects (CHD) are the most prevalent group of structural abnormalities at birth and one of the main causes of infant morbidity and mortality. Studies have shown a contribution of the copy number variation in the genesis of cardiac malformations. OBJECTIVES Investigate gene copy number variation (CNV) in children with conotruncal heart defect. METHODS Multiplex li...

The affinity of some chromosomal anomalies for certain types of congenital heart disease is well known, e.g. atrioventricular defects in Down's syndrome and coarctation of the aorta in Turner's syndrome. Many reports on several types of congenital heart disease in close or more distant family relationships have aroused suspicion that genetic factors may be important also in other patients. Repo...

We have reviewed our experience of 29 patients with the association of ventricular septal defect and aortic regurgitation, 27 of whom have been treated surgically. Our present approach to the surgical management is outlined and the embryology and pathological anatomy are reviewed. The most common cause of aortic regurgitation was a prolapsed aortic valve cusp, which occurred in 19 patients. Ane...

Many surgical approaches have been taken when closing ventricular septal defects after correcting transposition of the great arteries in order to avoid postoperative complete heart block. We describe a residual ventricular septal shunt that developed after repair using de Leval's method in a patient with congestive heart failure. The defect was closed transaortically without a complete heart bl...

Method 2013-2014: 23 congenital cardiac patients underwent heart transplantation. 13 of them: previous univentricular palliation: hypoplastic left heart syndrome (n = 8), dtransposition of great arteries+criss-cross-heart (n = 1), unbalanced atrioventricular septal defect (n = 1), pulmonary atresia+intact ventricular septum (n = 1) and grown-up patients (GUCH) (n = 2: 1 double-inlet-leftventric...

What is the major problem being addressed by this study? Children with single ventricle congenital heart lesions account for 25-40% of all neonatal cardiac deaths. Between 35-50% of these kids will experience an unanticipated acute cardio-respiratory arrest event within the first months of life, and 15% will not survive. This study addresses the current inability to accurately detect the onset ...

Background Pulmonary artery banding (PAB) is a technique of palliative surgical therapy used by congenital heart surgeons as a staged approach to operative correction of congenital heart defects. Materials and Methods We report 5- year experiences from January 2011 to January 2016 of Imam Reza Hospital center (a tertiary referral hospital in Mashhad city, North East of Iran) that consist of 50 ...

BACKGROUND Supraventricular arrhythmia (SVA) is a frequent clinical complication in adult patients with congenital heart disease (CHD). The aim of this study is prognostic evaluation of congenital heart defect complexity, performed cardiac surgery, initial functional impairment of the heart - NYHA > I, cyanosis, age and sex of the adult patients with CHD, presenting for the first time to an out...