Repeated oral administration of mexazolam, an anti-anxiety agent, may cause adverse effects such as gastric disturbance, drowsiness, and ataxia due to transiently high blood levels. Transdermal administration would avoid the systemic side effects and gastric disorders after oral administration. We have developed a matrix using ethylene-vinyl acetate (EVA), a heat-processible and flexible mat...

The aim of this study was to develop a derivative of chitosan as pharmaceutical excipient used in sustained-release matrix tablets of poorly soluble drugs. A water-soluble quaternary ammonium carboxymethylchitosan was synthesized by a two-step reaction with carboxymethylchitosan (CMCTS), decylalkyl dimethyl ammonium and epichlorohydrin. The elemental analysis showed that the target product with...

wear is a complicated phenomenon caused by the relative movement of two contacting surfaces compressed together by a normal force. prediction of the wear, in most cases, requires various experiments and microstructural characterization of the contacting surfaces. mathematical models based on physical concepts could provide considerable help in understanding the physical behavior and hence the p...

Thermoacoustic instabilities can arise in systems where unsteady heat release is favorably coupled with acoustic pressure oscillations. A modified Rijke tube with segments having different sections is found to have lower threshold levels of heat addition rate needed for exciting the fundamental acoustic mode of the tube. Experiments indicate that about 115 W of heating power is required to prod...

high temperatures are often encountered in almost all of the combustion systems, therefore, thermal radiation heat transfer can influence the droplets heat up rate and consequently their life time. in this paper, the effect of thermal radiation heat transfer is investigated for two cases of directional and spherically symmetric illuminations. the flow and temperature fields insdie and outside o...

the release rate of potassium (k) from micaceous minerals plays a significant role in supplying k to plants. the objective of this study was to determine the most appropriate kinetic equation to describe potassium release from micaceous minerals as influenced by organic acids. muscovite and phlogopite were made to react with 0, 500, 2000 and 4000 ?m solutions of oxalic, citric and malic acids f...

The height reached by a volcanic eruption column, together with the atmospheric wind regime, controls the dispersal of tephra. Column height is itself a function of vent radius, gas exit velocity, gas content of eruption products, and efficiency of conversion of thermal energy contained in juvenile material to potential and kinetic energy during the entrainment of atmospheric air. Different hei...

A transparent fire protective sol-gel coating deposited on wood has been evaluated using different tests, such as mass loss cone, mini single burning item and furnace tests. The heat release rate total during combustion, but also the flame spread behavior thermal protection performances of coatings have studied. Two processes to apply assessed show thickness dependence performance. When a thick...