Our data suggest that fine specificity of antihapten antibodies is a useful Mendelian marker of variable (V) genes. We found that some mouse strains (e.g., C57/BL6) consistently produced heteroclitic anti-(4-hydroxy-3-nitrophenyl)acetyl (NP) antibodies (relative affinity for related (4-hydroxy-5-iodo-3-nitrophenyl)acetyl and (4-hydroxy-3.5-dinitrophenyl)acetyl was always >2) while other strains...

We study the result by Bogdanov and Trevisan (FOCS, 2003), who show that under reasonable assumptions, there is no non-adaptive reduction that bases the average-case hardness of an NP-problem on the worst-case complexity of an NP-complete problem. We replace the hiding and the heavy samples protocol in [BT03] by employing the histogram verification protocol of Haitner, Mahmoody and Xiao (CCC, 2...

The nuclear-polarization (NP) energies for hydrogenlike heavy ions are calculated using the same collective model employed in [1, 2]. The transverse, as well as the Coulomb contributions, are considered in both the Feynman and Coulomb gauges. A considerable gauge violation is found when the ladder and cross diagrams only are taken into account. A schematic nuclear model with a separable interac...

I assume that most students have encountered Turing machines before. (Students who have not may want to look at Sipser’s book [3].) A Turing machine is defined by an integer k ≥ 1, a finite set of states Q, an alphabet Γ, and a transition function δ : Q×Γk → Q×Γk−1×{L, S,R}k where: • k is the number of (infinite, one-dimensional) tapes used by the machine. In the general case we have k ≥ 3 and ...

As a family of hormones with pleiotropic effects, natriuretic peptide (NP) system includes atrial NP (ANP), B-type NP (BNP), C-type NP (CNP), dendroaspis NP and urodilatin, with NP receptor-A (guanylate cyclase-A), NP receptor-B (guanylate cyclase-B) and NP receptor-C (clearance receptor). These peptides are genetically distinct, but structurally and functionally related for regulating circulat...

The diversity of virus-specific antibodies and of B cells among different individuals is unknown. Using single-cell cloning of antibody genes, we generated recombinant human monoclonal antibodies from influenza nucleoprotein-specific memory B cells in four adult humans with and without preceding influenza vaccination. We examined the diversity of the antibody repertoires and found that NP-speci...

Relativistic many-body calculations of energy levels, hyperfine constants, electric-dipole matrix elements and static polarizabilities for alkali-metal atoms. Abstract Removal energies and hyperfine constants of the lowest four ns, np 1/2 and np 3/2 states in Na, K, Rb and Cs are calculated; removal energies of the n=7–10 states and hyperfine constants of the n=7 and 8 states in Fr are also cal...

The immunoglobulin heavy chain (IGH) gene rearrangement in chronic lymphocytic leukemia (CLL) provides a unique molecular signature; however, we demonstrate that 26/198 CLL patients (13%) had more than one IGH rearrangement, indicating the power of molecular technology over phenotypic analysis. Single-cell PCR analysis and next-generation immuno-sequencing identified IGH-defined clones. In 23% ...

If all new particles are too heavy to be directly produced in the future Colliders, then the long sought New Physics (NP) could only appear in the form of new interactions, beyond those of the Standard Model (SM). Many of the processes that could be used to study these interactions, have already been discussed in the literature. Here, I first briefly discuss the list of all not yet excluded CP ...