نتایج جستجو برای: hek 293 cells

تعداد نتایج: 1389104  

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2005
Devadoss J Samuvel Lankupalle D Jayanthi Narayan R Bhat Sammanda Ramamoorthy

The serotonin transporter (SERT) is regulated by various signaling mechanisms that may operate to maintain appropriate levels of synaptic serotonin (5-HT). We demonstrate that one of the mitogen-activated protein kinases (MAPKs), p38 MAPK, regulates SERT. Treatment of rat midbrain synaptosomes with p38 MAPK-specific inhibitors, PD169316 [4-(4-fluorophenyl)-2-(4-nitrophenyl)-5-(4-pyridyl)-1H-imi...

Journal: :The Journal of biological chemistry 2002
Anastasios E Damdimopoulos Antonio Miranda-Vizuete Markku Pelto-Huikko Jan-Ake Gustafsson Giannis Spyrou

Thioredoxins (Trx) are a class of small multifunctional redox-active proteins found in all organisms. Recently, we reported the cloning of a mitochondrial thioredoxin, Trx2, from rat heart. To investigate the biological role of Trx2 we have isolated the human homologue, hTrx2, and generated HEK-293 cells overexpressing Trx2 (HEK-Trx2). Here, we show that HEK-Trx2 cells are more resistant toward...

2006
Cecilia Hurtado Michele Prociuk Thane G. Maddaford Elena Dibrov Nasrin Mesaeli Larry V. Hryshko Grant N. Pierce

Hurtado, Cecilia, Michele Prociuk, Thane G. Maddaford, Elena Dibrov, Nasrin Mesaeli, Larry V. Hryshko, and Grant N. Pierce. Cells expressing unique Na /Ca exchange (NCX1) splice variants exhibit different susceptibilities to Ca overload. Am J Physiol Heart Circ Physiol 290: H2155–H2162, 2006. First published January 6, 2006; doi:10.1152/ajpheart.00958.2005.—The Na /Ca exchanger (NCX) NCX1 exhib...

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