نتایج جستجو برای: hek293
تعداد نتایج: 3784 فیلتر نتایج به سال:
Allocryptopine and benzyltetrahydropalmatine block hERG potassium channels expressed in HEK293 cells
Background: Heme oxygenase-1 (HO-1) is a cytoprotective and antiapoptotic enzyme, which has been involved in maintaining cellular homeostasis, and plays an important protective role by modulating oxidative injury. Up-regulation of (HO-1) has contributed to tumorogenicity of some cancers. In this study we investigated the expression pattern of the HO-1, in five different human-derived cancer cel...
BACKGROUND Human cancer cells can transfer signaling molecules to neighboring and distant cells predisposing them to malignant transformation. This process might contribute to tumor progression and invasion through delivery of oncogenes or inhibitors of tumor suppressor genes, derived from the primary tumor cells, to susceptible target cells. The oncogenic potential of human cancer serum has be...
Cyclic acetals of ethylene glycol, cis-but-2-ene-1,4-diol and their dichlorocyclopropyl derivatives were synthesized. Compounds simultaneously containing the gem-dichlorocyclopropane 1,3-dioxacycloalkane cycles are shown to exhibit cytotoxic activity against HEK293, SH-SY5Y, HepG2, MCF-7, A549, Jurkat cell lines. The obtained results open up prospects for further studies antitumor 2-(2,2-dichlo...
Rabies is an infectious viral disease with a mortality rate close to 100%. Currently, there is a need to generate cheaper and more immunogenic vaccines for the effective prevention of rabies, mostly in developing countries. Virus-like particles have been widely used in viral vaccine production due to their high immunogenicity and safety during the production process. Rabies virus glycoprotein i...
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