A series of N-substituted pyrroles having phosphorylcholine with different methylene chain lengths between pyrrole group and phosphorylcholine group were synthesized and their electropolymerizations were performed in aqueous solution. The methylene chains were trimethylene (n = 3), pentamethylene (n = 5), nonamethylene (n = 9), and undecamethylene (n = 11), for 3-(1-pyrrolyl)propyl-2-(trimethyl...

We demonstrate here the generation of fluorescent superparamagnetic quantum clusters through a greener aqueous route by fusing highly fluorescent gold clusters with superparamagnetic nanoparticles. We conjugated transferrin onto the hybrid clusters to get cell accessibility and assessed their hemocompatibility and cytotoxicity. The ability of the clusters to selectively remove cancer cell lines...

A membrane-mimetic assembly incorporating surface bound heparin was fabricated as a system to improve the hemocompatibility of blood-contacting devices. As a model system, heparin was chemically modified by end-point conjugation to biotin and immobilized onto membrane-mimetic thin films via biotin-streptavidin interactions. Heparin surface density, determined by radiochemical titration, confirm...

Chitosan is a natural biodegradable polymer that recovered from marine shell wastes. It has been widely employed in anticancer, antioxidant, and antibacterial applications due to its outstanding qualities, including biological compatibility, muco-adhesivity, hemocompatibility, biodegradability. The contributions of this have established it with respect biomedical applications. distinct morpholo...

M. Basiaga, W. Walke, D. Nakonieczny, A. Hyla Faculty of Biomedical Engineering, Silesian University of Technology, Zabrze, Poland The purpose of this study was to evaluate the usefulness of TiO2 layer to improve hemocompatibility of 316LVM stainless steel. The TiO2 layers studied in this work were deposited from TiCl4 and H2O in a low-pressure Atomic Layer Deposition (ALD) reactor taking into ...